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Epigenetics of Aging

Editors: Tollefsbol, Trygve (Ed.)

  • Intended for those with interests ranging from the fundamental basis of aging to interventions in slowing the aging process or treating age-related diseases
  • Covers epigenetics as it relates to aging and age-related diseases, a relatively new field that is showing considerable promise in revolutionizing how the aging process is viewed
  • Provides coverage of not only established aspects of epigenetics and aging, but also new approaches and perceptions in this important area of research
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eBook $199.00
price for USA (gross)
  • ISBN 978-1-4419-0639-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-1-4419-0638-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-1-4899-8310-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Revealing the molecular basis of aging has been one of the most challenging aspects of medical science, and now the epigenetics of aging is in a Renaissance phase. This seminal work covers the fascinating role of epigenetics in aging, ranging from basic epigenetic processes of aging to epigenetic drugs that may intervene in allow aging and age-related diseases.

Epigenetics of Aging presents in-depth analyses of DNA methylation, histone modifications, RNA alterations, and chromosomal defects that impact the aging process. It also includes detailed essays describing the impact of epigenetics on aging, the epigenetics of age-related diseases, and future directions and perspectives on the epigenetics of aging.

With chapters authored by leading researchers in the field, this seminal book on the epigenetics of aging:

-Ranges from basic science to clinical practice

-Describes the importance of epigenetics in numerous diseases of aging such as cancer, Alzheimer’s disease, immune defects, and osteoporosis

-Includes the role of epigenetics in premature aging diseases such as progeria

-Highlights emerging aspects of epigenetics in aging, such as polycomb group genes and noncoding RNAs

-Covers sirtuins, chromatin alterations, and the role of epigenetic drift in aging

-Describes the impact of the environment and diet in modulating epigenetic processes during aging

Epigenetics of Aging is the first book in this exponentially expanding field, and will be an indispensable source of information for those with interests in epigenetics and/or aging. This authoritative core textbook for advanced students or medical scientists and practitioners details the fascinating and revolutionary field of the epigenetics of aging and covers the most recent advances that impact the longevity of living organisms.

Reviews

From the reviews:

“This nearly 500-pages thick book covers almost everything around the topic of how aging and age-related diseases might be affected by epigenetic processes. … Understanding the drifting and stochastic nature of aging is crucial for making any use of the epigenetic pathways to intervention, and for developing future directions in research. I surely recommend this book, which will help to open up many doors towards achieving that.” (Suresh I. S. Rattan, Biogerontology, Vol. 12, 2011)

Table of contents (26 chapters)

  • Epigenetics and the Aging Process

    Tollefsbol, Trygve O.

    Pages 1-8

  • Age-Related Genomic Hypomethylation

    Pogribny, Igor P. (et al.)

    Pages 11-27

  • Gene-Specific Hypermethylation in Aging

    Akintola, Adebayo D. (et al.)

    Pages 29-39

  • Aging and Non-sirtuin Histone Modifications

    Kadish, Inga

    Pages 41-50

  • Sirtuins and Aging

    Dong, Yuqing (et al.)

    Pages 51-75

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-1-4419-0639-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-1-4419-0638-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-1-4899-8310-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Epigenetics of Aging
Editors
  • Trygve Tollefsbol
Copyright
2010
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-1-4419-0639-7
DOI
10.1007/978-1-4419-0639-7
Hardcover ISBN
978-1-4419-0638-0
Softcover ISBN
978-1-4899-8310-7
Edition Number
1
Number of Pages
XIX, 469
Topics