Overview
- Covers the latest findings in the genetics of male reproductive cancers; specifically cancers of the prostate and testes
- Will cover the epidemiology of these cancers; model systems, pathology, molecular genetics, and inherited susceptibility
- Includes supplementary material: sn.pub/extras
Part of the book series: Cancer Genetics (CANGENETICS)
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Table of contents (11 chapters)
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Front Matter
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Epidemiology
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Front Matter
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Pathology
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Front Matter
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Molecular Genetics
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Front Matter
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Inherited Susceptibility
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Front Matter
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Back Matter
Keywords
About this book
Knowledge about cancer genetics is rapidly expanding, and has implications for all aspects of cancer research and treatment, including molecular causation, diagnosis, prevention, screening, and treatment.
Additionally, while cancer genetics has traditionally focused on mutational events that have their primary effect within the cancer cell, recently the focus has widened, with evidence of the importance of epigenetic events and of cellular interactions in cancer development. The role of common genetic variation in determining the range of individual susceptibility within the population is increasingly recognized, and is now being widely addressed using information from the Human Genome Project. These new research directions will highlight determinants of cancer that lie outside the cancer cell, suggest new targets for intervention, and inform the design of strategies for prevention in groups at increased risk.
Today, the NCI is putting more and more money into research into the genetics of cancer. The very first of the NCI’s stated research priorities is a project called The Cancer Genome Atlas. The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of genome analysis technologies, including large-scale genome sequencing. The NCI and the NHGRI (National Human Genome Research Institute, where the series editor is employed) have each committed $50 million over three years to the TCGA Pilot Project.
This book proposes cover the latest findings in the genetics of male reproductive cancers; specifically cancers of the prostate and testes. The volume will cover the epidemiology of these cancers; model systems, pathology, molecular genetics, and inherited susceptibility.
Editors and Affiliations
Bibliographic Information
Book Title: Male Reproductive Cancers
Book Subtitle: Epidemiology, Pathology and Genetics
Editors: William D. Foulkes, Kathleen A. Cooney
Series Title: Cancer Genetics
DOI: https://doi.org/10.1007/978-1-4419-0449-2
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag New York 2010
Hardcover ISBN: 978-1-4419-0448-5Published: 08 December 2009
Softcover ISBN: 978-1-4614-2511-3Published: 03 May 2012
eBook ISBN: 978-1-4419-0449-2Published: 17 December 2009
Series ISSN: 2626-1456
Series E-ISSN: 2626-1464
Edition Number: 1
Number of Pages: XIV, 346
Number of Illustrations: 18 b/w illustrations, 5 illustrations in colour
Topics: Cancer Research, Human Genetics, Oncology