Subcellular Biochemistry

Lipids in Health and Disease

Editors: Quinn, Peter, Wang, Xiaoyuan (Eds.)

  • The lipids represent targets for cell regulation
  • Their role in signaling processes is increasingly recognized
  • Their role in cell-cell recognition and social behavior of cells is identified
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About this book

Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.

Table of contents (22 chapters)

  • Transcriptional Regulation of Hepatic Fatty Acid Metabolism

    Guillou, Hervé (et al.)

    Pages 3-47

  • Modulation of Protein Function by Isoketals and Levuglandins

    Davies, Sean S.

    Pages 49-70

  • Signalling Pathways Controlling Fatty Acid Desaturation

    Mansilla, María Cecilia (et al.)

    Pages 71-99

  • Fatty Acid Amide Hydrolase: A Gate-Keeper of the Endocannabinoid System

    Fezza, Filomena (et al.)

    Pages 101-132

  • Modulation of Inflammatory Cytokines by Omega-3 Fatty Acids

    Kang, Jing X. (et al.)

    Pages 133-143

Buy this book

eBook $269.00
price for USA (gross)
  • ISBN 978-1-4020-8831-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $339.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-4020-8830-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $339.00
price for USA
  • ISBN 978-90-481-8001-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Lipids in Health and Disease
Editors
  • Peter Quinn
  • Xiaoyuan Wang
Series Title
Subcellular Biochemistry
Series Volume
49
Copyright
2008
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-1-4020-8831-5
DOI
10.1007/978-1-4020-8831-5
Hardcover ISBN
978-1-4020-8830-8
Softcover ISBN
978-90-481-8001-1
Series ISSN
0306-0225
Edition Number
1
Number of Pages
XXII, 598
Topics