Cancer Treatment and Research

Molecular Targeting and Signal Transduction

Editors: Kumar, Rakesh (Ed.)

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About this book

Our limited understanding of cellular regulatory signal-transduction-networks has been a barrier to progress in improving the overall cure-rate of human cancers. Delineation of the physiologic roles of the specific regulatory signaling components, with known association with metastatic phenotypes, is a highly promising area which will likely provide the next generation of targeted strategies in the future of molecular cancer medicine. These signaling components are likely to be used in diagnosis, prognosis, and as novel targets for therapeutic development.

This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general.

Table of contents (15 chapters)

  • Biology of the Epidermal Growth Factor Receptor Family

    Barnes, Christopher J. (et al.)

    Pages 1-13

  • Integrin Signaling in Cancer

    Goel, Hira Lal (et al.)

    Pages 15-31

  • Regulators of Vascular Endothelial Growth Factor Expression in Cancer

    Stoeltzing, Oliver (et al.)

    Pages 33-58

  • Integrin-Linked Kinase (ILK) in Combination Molecular Targeting

    Edwards, Lincoln A (et al.)

    Pages 59-75

  • P21-Activated Kinase 1: An Emerging Therapeutic Target

    Vadlamudi, Ratna K. (et al.)

    Pages 77-88

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-1-4020-7847-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-1-4020-7822-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-1-4757-7968-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Targeting and Signal Transduction
Editors
  • Rakesh Kumar
Series Title
Cancer Treatment and Research
Series Volume
119
Copyright
2004
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4020-7847-7
DOI
10.1007/b105352
Hardcover ISBN
978-1-4020-7822-4
Softcover ISBN
978-1-4757-7968-4
Series ISSN
0927-3042
Edition Number
1
Number of Pages
VIII, 331
Topics