Cancer Treatment and Research

Angiogenesis in Brain Tumors

Editors: Kirsch, Matthias, Black, Peter McL. (Eds.)

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About this book

This volume "Angiogenesis in Brain Tumors" is part of the book series "Cancer Treatment and Research" and offers a detailed overview of the biology of angiogenesis in the central nervous system, the role of angiogenesis in brain tumor development and growth, and anti-angiogenic therapeutic applications. Our understanding of the mutual relationship between tumor growth and concomitant neovascularization has provided important insights into the biology of brain tumors and contributed to the development of new treatment strategies. Many of the early experimental findings on angiogenesis were made using brain tumor models. This was largely due to the fact that brain tumors are among the highest vascularized tumors. In addition, until to date all efforts to develop efficient therapies for these highly malignant tumors have met with little if any success . The scientific evidence on the role of angiogenesis in tumor development accumulated until today has already let to the initiation of several clinical trials. Despite the fact that not all expectations have been fulfilled, the results available so far are promising and suggest that antiĀ­ angiogenic therapeutic strategies may be of benefit to our brain tumor patients in the near future. The volume is comprised of four sections . The first section is dedicated to the principles of angiogenesis in the central nervous system and gives an overview on the cellular, physiological and developmental processes of angiogenesis.

Table of contents (19 chapters)

  • Vasculogenesis and Angiogenesis

    Patan, Sybill

    Pages 3-32

  • Morphogenesis of Embryonic CNS Vessels

    Kurz, Haymo (et al.)

    Pages 33-50

  • Mathematical Modelling of Tumour-induced Angiogenesis: Network Growth and Structure

    Chaplain, Mark (et al.)

    Pages 51-75

  • Histologic Measures of Angiogenesis in Human Primary Brain Tumors

    Folkerth, Rebecca D.

    Pages 79-95

  • Angiogenesis in transgenic models of multistep angiogenesis

    Radovanovic, Ivan (et al.)

    Pages 97-114

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-4419-8871-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $319.00
price for USA
  • ISBN 978-1-4020-7704-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4613-4699-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Angiogenesis in Brain Tumors
Editors
  • Matthias Kirsch
  • Peter McL. Black
Series Title
Cancer Treatment and Research
Series Volume
117
Copyright
2004
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4419-8871-3
DOI
10.1007/978-1-4419-8871-3
Hardcover ISBN
978-1-4020-7704-3
Softcover ISBN
978-1-4613-4699-9
Series ISSN
0927-3042
Edition Number
1
Number of Pages
XIII, 358
Topics