Cancer Treatment and Research

Signal Transduction in Cancer

Editors: Frank, David A. (Ed.)

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eBook $169.00
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  • ISBN 978-0-306-48158-1
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Hardcover $289.00
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About this book

One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously.
This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents.
Series Editor comments:
"The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."

Reviews

"While the chapters in this book are necessarily brief, all are extensively referenced and msot authors have included historical as well as more recent references. Thus this book is an excellent summary of important signalling pathways in cancer that will be useful for students and researchers. It will serve as a resource for general and specialised knowledge regarding these pathways as well as a platform for more detailed research."
(Cancer Forum, 27:3)

Table of contents (14 chapters)

  • Growth, Survival and Migration: The Trk to Cancer

    Rubin, Joshua B. (et al.)

    Pages 1-18

  • The Role of Growth Factor Signaling in Malignancy

    Herbst, Roy S. (et al.)

    Pages 19-72

  • TGF-β Signaling Alterations in Cancer

    Bian, Yansong (et al.)

    Pages 73-94

  • Notch in Malignancy

    Ball, Douglas W. (et al.)

    Pages 95-121

  • cAMP Signaling in Cancer Genesis and Treatment

    Cho-Chung, Yoon S.

    Pages 123-143

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-0-306-48158-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4020-7340-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4757-7821-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Signal Transduction in Cancer
Editors
  • David A. Frank
Series Title
Cancer Treatment and Research
Series Volume
115
Copyright
2003
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-0-306-48158-1
DOI
10.1007/b101861
Hardcover ISBN
978-1-4020-7340-3
Softcover ISBN
978-1-4757-7821-2
Series ISSN
0927-3042
Edition Number
1
Number of Pages
VIII, 357
Topics