Proteins and Cell Regulation

Myb Transcription Factors: Their Role in Growth, Differentiation and Disease

Editors: Frampton, Jon (Ed.)

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4020-2869-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4020-2779-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-90-481-6720-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume represents the first collection of articles contributed by research leaders working on the Myb family of transcriptional regulatory proteins. In more than twenty chapters the authors discuss the range of biological processes and diverse cell types in which Myb proteins operate. Although concentrating on the three vertebrate Myb family members, homologues from lower species are also discussed because of the light they are able to shed on the evolution and function of these proteins. Individual chapters describe the involvement of Myb proteins, in particular c-Myb, in normal and diseased development and function of many tissues including haemopoietic cells, blood vessels, the gastrointestinal tract and the brain. Several chapters explore the mechanistic details of the action of Myb proteins, especially structural features, their interaction with DNA and other regulatory proteins, and the variety of genes that are regulatory targets for this group of transcription factors. This work will be of interest to those working directly in the field and also to the wider research community investigating the transcriptional regulation of development, differentiation and growth. The therapeutic potential of manipulating Myb function is also discussed making the book appealing to clinician scientists in several fields including haematology, oncology and cardiology.

Table of contents (21 chapters)

  • Evolution of Myb Proteins

    Davidson, Colin (et al.)

    Pages 1-33

  • Drosophila Myb

    Katzen, Alisa L.

    Pages 35-64

  • Essential And Diverse Roles For C-Myb Throughout T Cell Development

    Weston, Kathleen

    Pages 65-80

  • Potential Roles For C-Myb Thoughout Early Lymphocyte Development

    Bender, Timothy P.

    Pages 81-105

  • Involvement Of C-Myb In Red Cell And Megakaryocyte Development

    Vegiopoulos, Alexandros (et al.)

    Pages 107-131

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4020-2869-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4020-2779-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-90-481-6720-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Myb Transcription Factors: Their Role in Growth, Differentiation and Disease
Editors
  • Jon Frampton
Series Title
Proteins and Cell Regulation
Series Volume
2
Copyright
2004
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media B.V.
eBook ISBN
978-1-4020-2869-4
DOI
10.1007/978-1-4020-2869-4
Hardcover ISBN
978-1-4020-2779-6
Softcover ISBN
978-90-481-6720-3
Edition Number
1
Number of Pages
XXXI, 415
Topics