Signal Transducers and Activators of Transcription (STATs)

Activation and Biology

Editors: Sehgal, P., Levy, D. E., Hirano, T. (Eds.)

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eBook $339.00
price for USA (gross)
  • ISBN 978-94-017-3000-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
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  • Immediate eBook download after purchase
Hardcover $429.00
price for USA
  • ISBN 978-1-4020-1619-6
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Softcover $429.00
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  • ISBN 978-90-481-6421-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The year 2003 marks the tenth anniversary of the first use of the acronym "Stat" (also written "STAT") in the scientific literature for a family of transcription factors which rapidly transduce cytokine-and growth factor­ elicited signals from the plasma membrane to the cell nucleus thereby activating gene transcription (thus, . s. ignal Transducers and Activators of Transcription). From those beginnings, the field of STAT transcription factors, their related regulatory molecules and their biology has grown exponentially in many different directions. In recognition of the rapid growth and broad scope of the STAT transcription factor field today, and to celebrate the tenth anniversary of the use of this term in the scientific literature, Kluwer Academic Publishers B. V. requested us to compile a volume on STAT transcription factors that could serve as an overview of this burgeoning area. Thus, we wanted a volume that would serve as a reference for what is known about STAT proteins and their biology, would describe the current state of ongoing research in this broad area, and would look toward the future to try to predict the discoveries that lie ahead. Our charge was to seek out the very best experts in the field and to coax them to briefly summarize their areas of expertise.

Table of contents (48 chapters)

  • Introduction: A Brief History of the STATs and a Glance at the Future

    Darnell, James E.

    Pages 1-8

  • The STAT Protein Family

    Heim, Markus H.

    Pages 11-26

  • The Janus Kinase Protein Family

    Saharinen, Pipsa (et al.)

    Pages 27-42

  • Structural Bases of Receptor-JAK-STAT Interactions

    Heinrich, Peter C. (et al.)

    Pages 43-53

  • SOCS Proteins

    Starr, Robyn (et al.)

    Pages 55-73

Buy this book

eBook $339.00
price for USA (gross)
  • ISBN 978-94-017-3000-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $429.00
price for USA
  • ISBN 978-1-4020-1619-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $429.00
price for USA
  • ISBN 978-90-481-6421-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Signal Transducers and Activators of Transcription (STATs)
Book Subtitle
Activation and Biology
Editors
  • P. Sehgal
  • D. E. Levy
  • T. Hirano
Copyright
2003
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-94-017-3000-6
DOI
10.1007/978-94-017-3000-6
Hardcover ISBN
978-1-4020-1619-6
Softcover ISBN
978-90-481-6421-9
Edition Number
1
Number of Pages
XXIV, 746
Number of Illustrations and Tables
111 b/w illustrations, 17 illustrations in colour
Topics