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Aging of Cells in and Outside the Body

  • Book
  • © 2003

Overview

Editors:
  1. Sunil C. Kaul

    1. National Institute of Advanced Industrial, Science and Technology, Tsukuba Science City, Ibaraki, Japan

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  2. Renu Wadhwa

    1. National Institute of Advanced Industrial, Science and Technology, Tsukuba Science City, Ibaraki, Japan

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Biology of Aging and its Modulation (BIMO, volume 2)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-ix
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  2. Aging Outside the Body: Usefulness of the Hayflick System

    • Suresh I. S. Rattan
    Pages 1-8

  3. Genetics of Cellular Aging

    • Olivia M. Pereira-Smith, Paul Rookard, Johanna Echigo, James R. Smith
    Pages 9-26

  4. Aging of Fibroblasts

    • Dimitris Kletsas
    Pages 27-46

  5. Aging of Endothelial Cells

    • Tsutomu Kumazaki
    Pages 47-65

  6. In Vitro Senescence of Human Osteoblasts

    • Moustapha Kassem, Karin Stenderup, Jeannette Justesen, Marie Kveiborg
    Pages 67-84

  7. T Cell Immunosenescence

    • Graham Pawelec
    Pages 85-100

  8. Aging of Premature-Aging Syndrome Cells

    • Jan O. Nehlin
    Pages 101-119

  9. The p53 Pathway, Cancer and Aging

    • Antony W. Braithwaite, Sara J. Edwards
    Pages 121-149

  10. Regulation of Cellular Senescence by the Retinoblastoma Pathway

    • Therese M. Becker, Helen Rizos
    Pages 151-169

  11. Telomeres and Cellular Aging

    • Christian D. Toouli, Roger R. Reddel
    Pages 171-205

  12. Molecular Chaperones and Cellular Aging

    • Geneviève Morrow, Robert M. Tanguay
    Pages 207-223

  13. Cellular Senescence Pathways in Mouse and Human

    • Renu Wadhwa, Md. Kamrul Hasan, Sunil C. Kaul
    Pages 225-238

  14. Therapeutic Induction of Cellular Senescence: Nuclear Matrix in Senescence

    • Dai Ayusawa
    Pages 239-255

  15. Use of Hammerhead Ribozymes for Aging and Cancer

    • Hiroshi Minoshima, Eigo Suyama, Renu Wadhwa, Kazunari Taira
    Pages 257-267

  16. Back Matter

    Pages 269-276
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Keywords

About this book

This book provides updated knowledge on the basic features and mechanisms of cellular aging established since its first manifestation at cellular level 40 years ago. Contributions of genetic and environmental factors, failure of genetic and cellular repair mechanisms, and the epigenetic modifications determine the final lifespan of cells. This book also provides an understanding on how aging mechanisms in mice, a most frequently used model, differ with that of humans who receive better tumor surveillance because of stringent controls on aging mechanisms. It also appraises the use of modern technology for aging studies and its intervention. This book serves as an excellent reading on cellular aging for undergraduate students, researchers and experts of this area.

Editors and Affiliations

  • National Institute of Advanced Industrial, Science and Technology, Tsukuba Science City, Ibaraki, Japan

    Sunil C. Kaul, Renu Wadhwa

Bibliographic Information

  • Book Title: Aging of Cells in and Outside the Body

  • Editors: Sunil C. Kaul, Renu Wadhwa

  • Series Title: Biology of Aging and its Modulation

  • DOI: https://doi.org/10.1007/978-94-017-0669-8

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 2003

  • Hardcover ISBN: 978-1-4020-1375-1Published: 31 October 2003

  • Softcover ISBN: 978-90-481-6314-4Published: 25 December 2010

  • eBook ISBN: 978-94-017-0669-8Published: 14 March 2013

  • Edition Number: 1

  • Number of Pages: IX, 276

  • Number of Illustrations: 38 b/w illustrations

  • Topics: Cell Biology, Animal Anatomy / Morphology / Histology, Cancer Research, Oncology

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