Cell Engineering

Glycosylation

Editors: Al-Rubeai, Mohammed (Ed.)

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About this book

The analysis and modification of glycans of recombinant proteins continues to be active and challenging area of research and for the successful manufacture of these proteins. In Cell Engineering, volume 3: Glycosylation, Dr. Mohammed Al-Rubeai has compiled a group of articles that will provide research workers not only with reviews of the advances that have been made in all facets of the subject but with an in-depth assessment of the state of the art methodology and the various approaches for the improvement of glycoprotein production. Particularly important in this respect is the advances made in the development of genetically engineered host cell lines with novel glycosylation properties, as well as the integration of mass spectrophotometric analysis with separation techniques.

This volume is intended not only for research students and senior scientists in cell culture and glycobiology, but also for industrial biotechnologists and biochemical engineers interested in the production of therapeutic glycoproteins, virus vector and ex vivo expansion of human cells for medical treatment.

Table of contents (9 chapters)

  • Analysis of Glycans of Recombinant Glycoproteins

    Merry, T. (et al.)

    Pages 1-60

  • The Effect of Cell Culture Parameters on Protein Glycosylation

    Restelli, V. (et al.)

    Pages 61-92

  • Glycosylation of Recombinant IgG Antibodies and Its Relevance for Therapeutic Applications

    Jefferis, R.

    Pages 93-107

  • Cellular Modification for the Improvement of the Glycosylation Pathway

    Krummen, L. (et al.)

    Pages 109-130

  • Controlling Carbohydrates on Reconbinant Glycoproteins

    Jenkins, N. (et al.)

    Pages 131-148

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-0-306-47525-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-1-4020-0733-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-90-481-6068-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Glycosylation
Editors
  • Mohammed Al-Rubeai
Series Title
Cell Engineering
Series Volume
3
Copyright
2002
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-0-306-47525-2
DOI
10.1007/0-306-47525-1
Hardcover ISBN
978-1-4020-0733-0
Softcover ISBN
978-90-481-6068-6
Series ISSN
1389-6946
Edition Number
1
Number of Pages
VII, 235
Topics