Clinical efficacy of positron emission tomography

1. Front Matter

   Pages I-XII

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2. Introduction

   1. Introduction

      • W.-D. Heiss

      Pages 1-11

3. Brain

   1. Front Matter

      Pages 13-13

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   2. Ischemic Stroke Studied by 15O-Labeled Compounds: Misery Perfusion and Luxury Perfusion

      • J. C. Baron

      Pages 15-23

   3. Ischemic Disease Studied with 15O Labelled Compounds: Metabolic and Hemodynamic Disparities

      • R. S. J. Frackowiak

      Pages 25-36

   4. Brain Glucose Metabolism and Blood Flow in Ischemic Stroke

      • G. Pawlik, W.-D. Heiss, K. Wienhard, I. R. Hebold, P. Ziffling, W. Staffen et al.

      Pages 37-53

   5. Pet Studies in Internal Carotid Occlusion Patients: Base-Line Hemodynamic and Metabolic Alterations; Effects of Surgical Revascularization and Induced Arterial Hypertension

      • Y. Samson, J. C. Baron

      Pages 55-66

   6. Functional Evaluation of Extra-Intracranial Arterial Bypasses Using Pet and Repeated Bolus Administration of 15O Labeled Tracers

      • J. C. Depresseux, J. Lenelle, P. Merlot

      Pages 67-79

   7. Positron Emission Tomography in Cerebrovascular Disorders: Results and Perspectives

      • G. L. Lenzi, F. Fazio, C. Fieschi

      Pages 81-89

4. Brain

   1. Front Matter

      Pages 91-91

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   2. Changes of Cerebral Glucose Metabolism in Movement Disorders

      • F. J. Schuier

      Pages 93-100

   3. Progressive Supranuclear Palsy Studied by Pet

      • B. Mazière, J. C. Baron, C. Loc’h, H. Cambon, Y. Agid

      Pages 101-109

   4. Central Dopaminergic Mechanisms in Monkey and Man Studied by Positron Emission Tomography

      • S.-M. Aquilonius, P. Hartvig, K. L. Leenders, H. Lundqvist, B. Langström, J. Tedroff

      Pages 111-118

   5. Application of Pet in Clinical Brain Research

      • H.-J. Freund

      Pages 119-122

   6. SUMMARY of the Discussion on Brain I

      • C. Beckers

      Pages 123-124

5. Brain

   1. Front Matter

      Pages 125-125

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   2. Localizing Epileptic Foci by PET

      • K. Herholz, G. Pawlik, W. Staffen, P. Ziffling, I. Hebold, W.-D. Heiss

      Pages 127-136

   3. Clinical Applications of PET: Studies of Brain Glucose Metabolism in Pediatric Neurology

      • A. M. Goffinet, A. G. Devolder, A. Bol, C. Michel, M. Cogneau

      Pages 137-147

   4. The Value of PET in the Clinical Evaluation of Epileptic Patients

      • H.-G. Wieser

      Pages 149-156

6. Brain

   1. Front Matter

      Pages 157-157

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The series of workshops sponsored by the European Communities started with "Methodology of PET" at Hammersmith Hospital, London, in March 1984. This was followed by "Radiochemistry, Methodology and Standardization in PET" at the Service Hospitalier Frederic Joliot in Orsay, France, in March 1985. Both these meetings were, in the opinion of all participants, great successes, and it was agreed that such work­ shops should continue and be organized on the same basis. After these two workshops on the fundamentals of PET, time now is ripe to evaluate the clinical efficacy of PET investigations, and to discuss to what extend the information provided by this high technology and theoretical area has contributed to the understanding of disease mechanisms, leading to immediate clinical applications. As pointed out in the previous meetings, PET using short-lived radioisotopes produced in an on-line cyclotron is restricted to a few centers. Therefore, the topics studied so far were mainly of scientific interest and clinical problems were dealt with only marginally. Before this costly technique can be spread and new information made accessible to a broader clinical clientele, its clinical value must be demonstrat­ ed. So far, in the majority of studies, the central nervous system was the primary target organ, and PET has contributed a great deal to our understanding of brain physiology and pathology. Also on the heart, a substantial number of studies have been performed in various centers, but the application of PET to this organ is still somewhat limited.

• Public Health
• Tumor
• brain
• diseases
• heart
• magnetic resonance imaging (MRI)
• neoplasm
• neurology
• oncology
• positron emission tomography (PET)
• therapy
• tomography
• urology

`... an excellent review of a wide range of recent clinical research in PET. It will be a valuable addition to the libraries of nuclear medicine physicians, radiologists, neurologists, psychiatrists, and neurosurgeons who are interested in PET.'
American Journal of Roentgenology, December 1988.

• Max-Planck-Institute for Neurological Research, Cologne, Germany

  W.-D. Heiss, G. Pawlik, K. Herholz, K. Wienhard

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