Methods in Molecular Biology

Tumor Suppressor Genes

Volume 1: Pathways and Isolation Strategies

Editors: El-Deiry, Wafik S. (Ed.)

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eBook $149.00
price for USA (gross)
  • ISBN 978-1-59259-328-6
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  • Immediate eBook download after purchase
Hardcover $189.00
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  • ISBN 978-0-89603-986-5
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About this book

Powerful new tools are now available to discover and understand tumor suppressor genes (TSGs) and the biochemical mechanisms by which they control cancer development and progression. In Tumor Suppressor Genes, Volume 1: Pathways and Isolation Strategies, leading physician scientists and academic researchers review all the known tumor suppressor genes, explain how they work, and describe how they were discovered and isolated. In many cases, the authors discuss specific genes that are frequently involved in hereditary or sporadic cancers. They also provide a detailed guide to using powerful molecular genetic, cytogenetic, proteomic, and cell biological strategies to isolate and characterize novel tumor suppressor genes and their targets. The companion volume of this set, Tumor Suppressor Genes, Volume 2: Regulation, Function, and Medicinal Applications, demonstrates how best to explore the cell biology and biochemical function of such genes, and their encoded proteins, to study their physiological role in vivo, and to use information on TSGs to develop diagnostic and therapeutic strategies for cancer.
Comprehensive and authoritative, the two volumes of Tumor Suppressor Genes provide an unparalleled compilation of key data on all known tumor suppressor pathways and a treasury of techniques for their discovery, analysis, and uses in cancer therapeutics.

Table of contents (31 chapters)

  • Growth Control by the Retinoblastoma Gene Family

    Paggi, Marco G. (et al.)

    Pages 3-19

  • The APC Tumor Suppressor Pathway

    Morin, Patrice J. (et al.)

    Pages 21-40

  • Hereditary Breast and Ovarian Cancer Genes

    Scully, Ralph (et al.)

    Pages 41-57

  • Hereditary Colon Cancer Genes

    Grady, William M. (et al.)

    Pages 59-83

  • Patched, Hedgehog, and Skin Cancer

    Quinn, Anthony G. (et al.)

    Pages 85-95

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-59259-328-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-0-89603-986-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Tumor Suppressor Genes
Book Subtitle
Volume 1: Pathways and Isolation Strategies
Editors
  • Wafik S. El-Deiry
Series Title
Methods in Molecular Biology
Series Volume
222
Copyright
2003
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59259-328-6
DOI
10.1385/1592593283
Hardcover ISBN
978-0-89603-986-5
Series ISSN
1064-3745
Edition Number
1
Number of Pages
520
Number of Illustrations and Tables
73 b/w illustrations
Topics