Methods in Molecular Medicine

Suicide Gene Therapy

Methods and Reviews

Editors: Springer, Caroline J. (Ed.)

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About this book

Suicide gene therapy has become a major element in anticancer gene therapy and holds great promise for the future. In Suicide Gene Therapy: Methods and Reviews, prominent researchers and clinicians comprehensively detail the theory and practice of this exciting and elegant therapeutic approach. In their multidisciplinary treatment, the authors cover all the major aspects of suicide gene therapy, including the design and use of vectors in gene transduction, various enzyme and prodrug systems, the mechanistic analysis of the bystander effect, the design and synthesis of prodrugs, the immunological implications, and its clinical impact. They also describe and expound upon all the cutting-edge methods needed to explore, study, and advance understanding of the basic biology underlying gene therapy. Each fully tested method includes step-by-step instructions, a discussion of the principle behind the technique, equipment and reagent lists, tips on troubleshooting and avoiding pitfalls, and notes on the interpretation and use of results.
Authoritative and up-to-date, Suicide Gene Therapy: Methods and Reviews not only summarizes our knowledge of suicide gene therapy today, but also provides the experimental means to advance its future development and therapeutic applications.

Reviews

"This is a good book for those working in the area of suicide gene therapy that can serve both as a reference to senior investigators as well as a primer to new lab members and researchers outside the field who are trying to get a flavor of the state of the field."-Doody's Health Sciences Book Review Journal

"...an extensive review of the theoretical background of suicide gene therapy that covers all major aspects..." - ChemBioChem

"Authoritative and up-to-date...provides the experimental means to advance its future development and therapeutic applications." - Anticancer Research

Table of contents (27 chapters)

  • Introduction to the Background, Principles, and State of the Art in Suicide Gene Therapy

    Niculescu-Duvaz, Ion (et al.)

    Pages 1-27

  • Introduction to Vectors for Suicide Gene Therapy

    Springer, Caroline J.

    Pages 29-45

  • Construction of VNP20009

    Low, Kenneth Brooks (et al.)

    Pages 47-59

  • Nonreplicating DNA Viral Vectors for Suicide Gene Therapy

    Yamamoto, Masato (et al.)

    Pages 61-70

  • Replication-Selective Oncolytic Adenoviruses

    Halldén, Gunnel (et al.)

    Pages 71-90

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-59259-429-0
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-0-89603-971-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA
  • ISBN 978-1-61737-283-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Suicide Gene Therapy
Book Subtitle
Methods and Reviews
Editors
  • Caroline J. Springer
Series Title
Methods in Molecular Medicine
Series Volume
90
Copyright
2004
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59259-429-0
DOI
10.1385/1592594298
Hardcover ISBN
978-0-89603-971-1
Softcover ISBN
978-1-61737-283-4
Series ISSN
1543-1894
Edition Number
1
Number of Pages
XIV, 555
Topics