Current Clinical Oncology

Chronic Leukemias and Lymphomas

Biology, Pathophysiology, and Clinical Management

Editors: Schiller, Gary J. (Ed.)

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eBook $149.00
price for USA (gross)
  • ISBN 978-1-59259-308-8
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Hardcover $259.00
price for USA
  • ISBN 978-0-89603-907-0
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Softcover $199.00
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  • ISBN 978-1-4684-9732-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

In the last decade advances in basic and clinical research on chronic leukemias and lymphomas-slowly progressive diseases of the blood and bone marrow-have produced a host of remarkable therapies, including the use of unique small molecules targeted at specific genetic lesions: pro-apoptotic drugs, monoclonal antibodies, and adoptive immunotherapy. In Chronic Leukemias and Lymphomas: Biology, Pathophysiology, and Clinical Management, a panel of recognized experts in hematological oncology describe the unique biological features of indolent hematologic neoplasms, providing powerful insight into their clinical manifestation, highlighting potential targets for novel therapies, and distinguishing these disorders from aggressive lymphoma and Hodgkin's disease. In their integrated surveys of chronic myeloproliferative and lymphoproliferative disorders, the authors place special emphasis on such unique entities as prolymphocytic leukemias and cutaneous lymphomas. Among the disease models considered for chronic lymphocytic leukemia, low-grade lymphoma, and chronic myelogenous leukemia are impairments of the apoptotic mechanisms, as well as specific molecular events that initiate proliferation. Both models of oncogenesis may lead to novel therapeutic targets, such as purine nucleoside analogs for chronic lymphocytic leukemias, monoclonal antibodies for follicular lymphomas, and STI-571 (Gleevec) for chronic myelogenous leukemia.
Comprehensive and up-to-date, Chronic Leukemias and Lymphomas: Biology, Pathophysiology, and Clinical Management is a unique book devoted to summarizing both the basic biology and the practical management of myeloproliferative disorders, low grade lymphomas, and chronic leukemias, distinguishing these disorders from large-cell lymphoma and Hodgkin's disease. Special emphasis is given to the mechanisms of disease progression with authoritative insights into the promising new era of antineoplastic pharmacology.

Reviews

"The book summarizes well the most recent insights into molecular pathogenesis of chronic hematologic diseases including chronic leukemias, myelo- and lymphoproliferative diseases, lymphomas and multiple myeloma, and their relevance for assessment of prognosis and management decisions. The results of trials evaluating novel targeted therapies are presented, succinctly providing reader with the most current information...This is a very useful book since it covers the most recent achievements and "hot" topics in chronic hematologic diseases in a concise format. The up-to-date information that it provides might not be available in larger textbooks, and thus it is highly recommended for practitioners and researchers." -Doody's Health Sciences Book Review Journal

Table of contents (12 chapters)

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-59259-308-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-0-89603-907-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA
  • ISBN 978-1-4684-9732-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Chronic Leukemias and Lymphomas
Book Subtitle
Biology, Pathophysiology, and Clinical Management
Editors
  • Gary J. Schiller
Series Title
Current Clinical Oncology
Copyright
2003
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-59259-308-8
DOI
10.1007/978-1-59259-308-8
Hardcover ISBN
978-0-89603-907-0
Softcover ISBN
978-1-4684-9732-8
Series ISSN
2364-1134
Edition Number
1
Number of Pages
X, 342
Number of Illustrations and Tables
31 b/w illustrations
Topics