Methods in Molecular Medicine

Meningococcal Vaccines

Methods and Protocols

Editors: Pollard, Andrew J., Maiden, Martin C.J. (Eds.)

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About this book

The development of a comprehensive vaccine against Neisseria meningitidis, the causative agent of meningococcal disease, has remained elusive because of bacterial diversity and immunologic evasion. In Meningococcal Vaccines: Methods and Protocols, Andrew Pollard and Martin Maiden have assembled an impressive collection of the latest molecular and cellular techniques for the development, evaluation, and implementation of vaccines to be used against this dreaded disease. The contributors-leading scientists, clinicians, and public health physicians-describe in detail the many approaches to vaccine design, as well as the assessment of immune response to vaccine candidates and novel vaccine formulations. They also present as a test case the recent implementation of a new meningococcal vaccine in the United Kingdom. A companion volume, Meningococcal Disease: Methods and Protocols, contains detailed methods for diagnostic microbiology, bacterial characterization, epidemiology, host-pathogen interactions, and clinical studies.
Timely and comprehensive, Meningococcal Vaccines: Methods and Protocols provides the scientist, public health physician, epidemiologist, clinical microbiologist, and clinician with the essential tools to lay bare the secrets of the meningococcus and to develop, evaluate, and implement successful new meningococcal vaccines.

Reviews

"This volume is an impressive collection of the latest techniques in the development, evaluation and application of meningococcal vaccines. The easy-to-follow protocols each preceded by a brief introduction into the topic were provided by leading scientists in the field. Andrew Pollard and Martin Maiden did a great job in assembling these protocols into one volume - a work we all in the meningococcal field have waited for." - International Journal of Medical Microbiology.

"The strength of this text is that it provides a key reference source, enabling researchers in the field to avoid reinventing the wheel. The text also provides the basis for the development of new ideas. Each chapter takes a step-by-step approach with clearly set out notes highlighting the problem areas. All the chapters have comprehensive bibliographies, and are well structured. The text is easily accessible and is recommended to those who are seeking to critically appraise the field of meningococcal vaccines." - Epidemiology and Infection

"This book and its accompanying volume are well produced, easy to read and well edited. Andrew Pollard and Martin Maiden are to be congratulated in bringing together in these two volumes an enormous amount of information about this very important topical infection." -Molecular Biotechnology

Table of contents (28 chapters)

  • Meningococcal Vaccines and Vaccine Developments

    Feavers, Ian M.

    Pages 1-22

  • Immune Response and Host-Pathogen Interactions

    Pollard, Andrew J. (et al.)

    Pages 23-39

  • Purification of Capsular Polysaccharide

    Yang, Qingling (et al.)

    Pages 41-47

  • Protein-Polysaccharide Conjugation

    Guo, Zhongwu (et al.)

    Pages 49-54

  • N-Propionylation

    Guo, Zhongwu (et al.)

    Pages 55-60

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-59259-148-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-0-89603-801-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4899-4225-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Meningococcal Vaccines
Book Subtitle
Methods and Protocols
Editors
  • Andrew J. Pollard
  • Martin C.J. Maiden
Series Title
Methods in Molecular Medicine
Series Volume
66
Copyright
2001
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-59259-148-0
DOI
10.1385/1592591485
Hardcover ISBN
978-0-89603-801-1
Softcover ISBN
978-1-4899-4225-8
Series ISSN
1543-1894
Edition Number
1
Number of Pages
XVII, 421
Number of Illustrations and Tables
20 b/w illustrations
Topics