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Endocrinology of Breast Cancer

  • Book
  • © 1999

Overview

Editors:
  1. Andrea Manni

    1. College of Medicine, The Pennsylvania State University, Hershey, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Contemporary Endocrinology (COE, volume 11)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-x
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  2. Hormonal Control of Mammary Development and Growth

    1. Front Matter

      Pages 1-1
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    2. Hormonal Control of Normal Breast Morphology and Function

      • Richard E. Blackwell, Karen R. Hammond
      Pages 3-20

    3. Interactions Between Estradiol and Progesterone in Normal Breast

      • Geneviève Plu-Bureau, Philippe Touraine, Pierre Mauvais-Jarvis
      Pages 21-37

    4. Expression and Regulation of Insulin-like Growth Factors and Their Binding Proteins in the Normal Breast

      • Monica M. Richert, Teresa L. Wood
      Pages 39-52

  3. Carcinogenesis

    1. Front Matter

      Pages 53-53
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    2. Estrogens and Breast Cancer

      • Heather Spencer Feigelson, Brian E. Henderson
      Pages 55-67

    3. Androgens, Estrogens, and Breast Cancer Risk

      • V. H. T. James
      Pages 69-77

    4. Local Estrogen Production

      • Rajeshwar Rao Tekmal, Richard J. Santen
      Pages 79-92

    5. Oncogenes and Mammary Carcinogenesis

      • Maria Luisa Veronese, Florencia Bullrich, Carlo M. Croce
      Pages 93-108

    6. Categorization of Breast Cyst Fluid and Breast Cancer Risk

      • Luigi Dogliotti, Pasquale Caraci
      Pages 109-116

  4. Tumor Progression

    1. Front Matter

      Pages 117-117
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    2. The Role of Tumor Suppressor Genes in Breast Cancer Progression

      • Robert Callahan
      Pages 119-132

    3. Oncogene Activation and Breast Cancer Progression

      • Richard J. Pietras, Mark D. Pegram
      Pages 133-153

    4. Interactions Between Stroma and Epithelium in Breast Cancer

      • Kevin J. Cullen, Sahana S. Kaup, Audrey A. Rasmussen
      Pages 155-168

    5. Role of Angiogenesis in the Transition to Hormone Independence and Acquisition of the Metastatic Phenotype

      • Francis G. Kern
      Pages 169-186

    6. Role of the IGF System in Breast Cancer Proliferation and Progression

      • A. V. Lee, D. Yee
      Pages 187-203

    7. Prognostic and Predictive Factors in Breast Cancer

      • Jan G. M. Klijn, Els M. J. J. Berns, John A. Foekens
      Pages 205-220

    8. Role of the Polyamine Pathway in the Natural History of Breast Cancer

      • Andrea Manni
      Pages 221-230

  5. Estrogen, Progestins, and Prolactin in Breast Cancer Biology: Targets for Treatment

    1. Front Matter

      Pages 231-231
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Keywords

About this book

A cutting-edge review of how derangements in the hormonal and growth factor mechanisms controlling normal mammary development lead to breast cancer. Drawing on the multidisciplinary expertise of leading authorities, the book highlights the roles of oncogenes and tumor suppressor genes, spelling out the importance of autocrine/paracrine loops (e.g., stromal epithelial interactions) in supporting breast cancer cell proliferation and the progression to hormone independence. The book's many prominent contributors also illuminate significant recent advances in the biochemistry and physiology of hormone receptors and review the state-of -the-art in the endocrine therapy of breast cancer. Endocrinology of Breast Cancer provides a unique integrated overview of the most significant basic and clinical developments concerning the hormonal aspects of breast cancer.


Reviews

"A variety of topics are covered, including carcinogenesis, tumor progression, therapeutic options, and benign breast disease. The section divisions of the book make it easy to locate topics of interest. Each chapter has an extensive list of references for further study. Parts IV and V are very thorough in reviewing targets for therapy and endocrine therapy. These chapters provide a good basis from which to understand the development of endocrine therapies. The discussion of normal breast physiology and development is beneficial for the less specialized physician and helps to round out the discussion. "-Doody's Health Science Book Review Journal

"...an invaluable resource for both basic scientists and clinicians who need to update their knowledge about breast cancer biology..."-Cell Biology International 2000

"The authors have succeeded in exploring the most important cell physiology and molecular biology issues pertaining to m endocrinology of breast cancer. For example, there are detailed chapters exploring the relationship between both oncogenes and tumor suppressor genes and breast cancer induction and progression. In addition this volume contains detailed, yet concise, chapters pertaining to the prediction of breast cancer, chemoprevention, and the most novel hormonal treatment strategies. The editor and the authors have clearly worked together to create a focused, yet thorough chapters with minimal overlap, and maximum synergy among chapters" -Quarterly Review of Biology

"...will serve as a comprehensive reference for students, physicians in training, practitioners and investigators....I found the book most helpful as an encyclopedia description of the subject matter. ...I give DR. Manni high marks for having pulled it all together. The goal was to furnish a new state-of-the-art, reference text to fill an important gap." -Elsevier Science

"If you are very interested in the endocrinology of breast development and disease, there probably is no other book available that deals with this area as completely and as currently as this one. Thus, it is a significant contribution to the breast literature."-Modern Pathology

Editors and Affiliations

  • College of Medicine, The Pennsylvania State University, Hershey, USA

    Andrea Manni

Bibliographic Information

  • Book Title: Endocrinology of Breast Cancer

  • Editors: Andrea Manni

  • Series Title: Contemporary Endocrinology

  • DOI: https://doi.org/10.1007/978-1-59259-699-7

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1999

  • Hardcover ISBN: 978-0-89603-591-1Published: 15 January 1999

  • Softcover ISBN: 978-1-4757-5139-0Published: 14 April 2013

  • eBook ISBN: 978-1-59259-699-7Published: 15 January 1999

  • Series ISSN: 2523-3785

  • Series E-ISSN: 2523-3793

  • Edition Number: 1

  • Number of Pages: X, 392

  • Topics: Endocrinology, Oncology

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