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Highly Selective Neurotoxins

Basic and Clinical Applications

  • Book
  • © 1998

Overview

Editors:
  1. Richard M. Kostrzewa

    1. Department of Pharmacology, Quillen College of Medicine, East Tennessee State University, Johnson City, USA

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Part of the book series: Contemporary Neuroscience (CNEURO)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xii
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  2. 6-Hydroxydopamine and Related Catecholaminergic Neurotoxins

    • C. LeRoy Blank, Russell J. Lewis, Roland E. Lehr
    Pages 1-18

  3. The Use of Neurotoxins to Lesion Catecholamine-Containing Neurons to Model Clinical Disorders

    • Charles R. Breese, George R. Breese
    Pages 19-73

  4. 6-Hydroxydopamine as a Tool for Studying Catecholamines in Adult Animals

    • Michael J. Zigmond, Kristen A. Keefe
    Pages 75-107

  5. 6-Hydroxydopa, a Catecholamine Neurotoxin and Endogenous Excitotoxin at Non-NMDA Receptors

    • Richard M. Kostrzewa
    Pages 109-129

  6. 2-Chloroethylamines (DSP4 and Xylamine)

    • Guillermo Jaim-Etcheverry
    Pages 131-140

  7. MPTP

    • Joyce E. Royland, J. William Langston
    Pages 141-194

  8. Haloperidol-Derived Pyridinium Metabolites

    • Cornelis J. Van der Schyf, Etsuko Usuki, Susan M. Pond, Neal Castagnoli Jr.
    Pages 195-210

  9. The Neurotoxic Effects of Continuous Cocaine and Amphetamine in Habenula

    • Gaylord Ellison
    Pages 211-233

  10. Evidence for and Mechanism of Action of Neurotoxicity of Amphetamine Related Compounds

    • R. Lew, J. E. Malberg, George A. Ricuarte, Lewis S. Seiden
    Pages 235-268

  11. Molecular Mechanisms of Action of 5,6- and 5,7-Dihydroxytryptamine

    • Tahereh Tabatabaie, Glenn Dryhurst
    Pages 269-291

  12. Use of 5,6- and 5,7-Dihydroxytryptamine to Lesion Serotonin Neurons

    • Michael R. Pranzatelli
    Pages 293-311

  13. Selective Cholinergic Neurotoxins

    • Thomas J. Walsh, Pamela E. Potter
    Pages 313-327

  14. Glutamatergic Receptor Agonists and Brain Pathology

    • Ewa M. Urbanska, Andrzej Dekundy, Zdzislaw Kleinrok, Waldemar A. Turski, Stanislaw J. Czuczwar
    Pages 329-354

  15. Neurotoxiciy of NMDA Receptor Antagonists

    • Sunita Rajdev, Frank R. Sharp
    Pages 355-384

  16. Toxic Vanilloids

    • Arpad Szallasi
    Pages 385-398

  17. Back Matter

    Pages 399-404
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Keywords

About this book

Expert researchers critically review and evaluate the most common and important neurotoxins used today in neuroscience research. Each informative chapter thoroughly describes the significant mechanisms of action of a neurotoxin, as well as fully discussing the limits on their use and their clinical applicability. Several clinically oriented chapters are significant for neurologists treating Parkinsonism, for psychiatrists treating drug abuse and neurodegenerative disorders, and for primary care physicians treating patients with appetite suppressants. Highly Selective Neurotoxins provides all the basic knowledge needed to obtain a predictable experimental outcome with these neurotoxins.

Editors and Affiliations

  • Department of Pharmacology, Quillen College of Medicine, East Tennessee State University, Johnson City, USA

    Richard M. Kostrzewa

Bibliographic Information

  • Book Title: Highly Selective Neurotoxins

  • Book Subtitle: Basic and Clinical Applications

  • Editors: Richard M. Kostrzewa

  • Series Title: Contemporary Neuroscience

  • DOI: https://doi.org/10.1007/978-1-59259-477-1

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1998

  • Hardcover ISBN: 978-0-89603-465-5Published: 30 October 1997

  • Softcover ISBN: 978-1-61737-047-2Published: 19 November 2010

  • eBook ISBN: 978-1-59259-477-1Published: 30 October 1997

  • Edition Number: 1

  • Number of Pages: XII, 404

  • Number of Illustrations: 9 b/w illustrations

  • Topics: Neurology, Neurosciences

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