Molecular Biology of Diabetes

I. Autoimmunity and Genetics; Insulin Synthesis and Secretion

Editors: Draznin, Boris, LeRoith, Derek (Eds.)

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About this book

In a rapidly evolving and extremely important area of medical science, it is often difficult for the student, teacher, and researcher to keep abreast of all the important advances. The purpose of Molecular Biology ofDiabetes, Parts I and II is to bring to these individuals the latest knowledge of diabetes-related research in a comprehensive, yet concise manner. To this end, we have assembled chapters, written by most of the world's experts in the field, that we believe compre­ hensively survey and synthesize a coherent understanding of the subject. Studies of the etiology of type I and type II diabetes are extremely exciting and essential, since we hope to one day prevent the disease using gene therapy. These aspects are covered in Molecular Biology of Diabetes: I. Autoimmunity and Genetics; Insulin Synthesis and Secretion. In type II diabetes, an abnormality in pancreatic secretion exists concomitantly with peripheral insulin resistance. This abnor­ mality of insulin secretion is believed to be related to a defect(s) in glucose sensing. Uncoupling of glucose sensing from insulin secre­ tion may be the crucial step in the pathogenesis of noninsulin-depen­ dent diabetes. In this volume, we have invited authors to describe their studies on all known factors affecting ~-cell function, including autoimmunity and genetics of diabetes, as well as molecular mecha­ nisms of insulin synthesis and secretion. In the last few years, the most rapidly advancing area of research in diabetes has been, in fact, related to insulin action.

Reviews

This is an essential book for a medical library to have, and it is a welcome addition to the library of investigators in the field. Specialists in diabetes will also find this book very useful. - Kevan Herold, MD for Doody's Health Science Book Review Journal

Table of contents (16 chapters)

  • Molecular Targets of the Autoimmunity of Type I Diabetes

    Pietropaolo, Massimo (et al.)

    Pages 1-33

  • Murine Transgenic Models of IDDM

    Gu, Danling (et al.)

    Pages 35-47

  • Pancreatic Islet Transplantation

    Gill, Ronald G.

    Pages 49-67

  • Pathogenesis of Autoimmune Diabetes

    Calcinaro, Filippo (et al.)

    Pages 69-90

  • Insulin Gene Structure and Regulation

    German, Michael S.

    Pages 91-117

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4612-0241-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-0-89603-286-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4612-6677-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Biology of Diabetes
Book Subtitle
I. Autoimmunity and Genetics; Insulin Synthesis and Secretion
Editors
  • Boris Draznin
  • Derek LeRoith
Copyright
1994
Publisher
Humana Press
Copyright Holder
Humana Press Inc.
eBook ISBN
978-1-4612-0241-7
DOI
10.1007/978-1-4612-0241-7
Hardcover ISBN
978-0-89603-286-6
Softcover ISBN
978-1-4612-6677-8
Edition Number
1
Number of Pages
XV, 404
Topics