Neurobiology of the Trace Elements

1. Front Matter

   Pages I-XIX

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2. Behavioral Toxicology of Heavy Metals

   • Bernard Weiss

   Pages 1-50

3. Cadmium Toxicity and Neural Cell Damage

   • Björn Arvidson

   Pages 51-78

4. Cadmium and Teratogenesis of the Central Nervous System

   • Louis J. Pierro

   Pages 79-96

5. Neurobiological And Behavioral Effects Of Lead

   • Ted L. Petit, Dennis P. Alfano

   Pages 97-139

6. Neurotoxic Effects of Lead

   • P. McConnell

   Pages 141-166

7. Neurological Consequences of Manganese Imbalance

   • Satya V. Chandra

   Pages 167-196

8. Mercury and Abnormal Development of the Fetal Brain

   • B. H. Choi

   Pages 197-235

9. Aluminum Neurobehavioral Toxicology

   • Ted L. Petit

   Pages 237-274

10. Lithium Effects on Bipolar (Manic-Depressive) Illness and Other Behavior

    • Michael H. Sheard

    Pages 275-284

11. Trace Elements in Neurobiology-Conclusions

    • R. M. Smith, I. E. Dreosti

    Pages 285-290

12. Back Matter

    Pages 291-300

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F. Macfarlane Burnet I have been an interested onlooker for many years at research on the biology of trace elements, particularly in its bearing on the pas­ toral and agricultural importance of copper, zinc, cobalt, and mo­ lybdenum deficiencies in the soil of various parts of Australia. More recently I have developed a rather more specific interest in the role of zinc, particularly in relation to the dominance of zinc metalloenzymes in the processes of DNA replication and repair, and its possible significance for human pathology. One area of special significance is the striking effect of zinc deficiency in the mother in producing congenital abnormalities in the fetus. The fact that several chapters in the present work are concerned with this and other aspects of zinc deficiency is, I fancy, the editors jus­ tification for inviting me to write this foreword. In reading several of the chpaters before publication, my main impression was of the great potential importance of the topic of trace metal biology in both its negative and positive aspects-the effects of deficiency of essential elements and the toxicity of such pollutants of the modern world as lead or mercury mainly as or­ ganic compounds.

• Nervous System
• biology
• brain
• central nervous system
• heavy metal
• lead
• mercury
• neurobiology
• neuropharmacology
• neurotoxicology
• pollutants
• research
• soil
• toxicity
• toxicology

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