Mitochondrial Dysfunction in Neurodegenerative Disorders

Editors: Reeve, A.K., Krishnan, K.J., Duchen, M.R., Turnbull, D.M. (Eds.)

  • The book will contain contributions from a number of leading international scientists in the field so that the reader will have access to the most current research in a concise and logical format
  • Will contain schematic diagrams, results images and tables to assist the reader in the understanding of some of the results and discussions of the book
  • Will cover all aspects of the potential contribution of mitochondria to these diseases from the simple to the more complex, both in terms of experimental data and literature review. This will assist the reader in understanding new and perhaps difficult concepts
  • Contains experimental methods and as well as results. Any readers with a similar interest may find methods beneficial to their research interests
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eBook $169.00
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  • ISBN 978-0-85729-701-3
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  • Immediate eBook download after purchase
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About this book

As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease and multiple sclerosis and the mechanisms which lead from mitochondrial dysfunction to neurodegeneration. Mitochondrial Dysfunction in Neurodegenerative Disorders brings together contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of these diseases, guiding the reader through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, to the consequences of this dysfunction on neuronal function before finishing with the modelling of these disorders and discussion of new potential therapeutic targets. Mitochondrial Dysfunction in Neurodegenerative Disorders provides an accessible, authoritative guide to this important area for neurologists; research and clinical neuroscientists; neuropathologists; and residents with an interest in clinical research.

Table of contents (13 chapters)

  • An Introduction to Mitochondria

    Reeve, Amy Katherine (et al.)

    Pages 3-18

  • Neurodegeneration in Primary Mitochondrial Disorders

    Lax, Nichola (et al.)

    Pages 21-41

  • Mutations in Nuclear Genes That Affect Mitochondrial Function in Parkinson’s Disease

    Charlesworth, Gavin (et al.)

    Pages 43-61

  • Common mtDNA Polymorphisms and Neurodegenerative Disorders

    Elson, Joanna L. (et al.)

    Pages 63-78

  • mtDNA Mutations in Brain Aging and Neurodegeneration

    Krishnan, Kim Jennifer (et al.)

    Pages 79-91

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-0-85729-701-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Mitochondrial Dysfunction in Neurodegenerative Disorders
Editors
  • Amy K. Reeve
  • Kim Jennifer Krishnan
  • Michael R. Duchen
  • Doug M. Turnbull
Copyright
2012
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London Limited
eBook ISBN
978-0-85729-701-3
DOI
10.1007/978-0-85729-701-3
Edition Number
1
Number of Pages
XXI, 242
Number of Illustrations and Tables
8 b/w illustrations, 12 illustrations in colour
Topics