Cardiovascular Molecular Morphogenesis

Myofibrillogenesis

Editors: Dube, Dipak K. (Ed.)

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About this book

Myofibrillogenesis has been studied extensively over the last 100 years. Until recently, we have not had a comprehensive understanding of this fundamental process. The emergence of new technologies in molecular and cellular biology, combined with classical embryology, have started to unravel some of the complexities of myofibril assembly in striated muscles. In striated muscles, the contractile proteins are arranged in a highly ordered three dimensional lattice known as the sarcomere. The assembly of a myofibril involves the precise ordering of several proteins into a linear array of sarcomeres. Multiple isoforms in many of these proteins further complicate the process, making it difficult to define the precise role of each component. This volume has been compiled as a comprehensive reference on myofibrillogenesis. In addition, the book includes reviews on myofibrillar disarray under various pathological conditions, such as familial hypertrophic cardiomyopathy (FHC), and incorporates a section on the conduction system in the heart. Much of the information in this volume has not been described elsewhere. Presented in a manner to be of value to students and teachers alike, "Myofibrillogenesis" will be an invaluable reference source for all in the fields of muscle biology and heart development.

Table of contents (14 chapters)

  • Myofibrillogenesis in Cardiac Muscle

    Sanger, Joseph W. (et al.)

    Pages 3-20

  • Dynamics of Contractile Proteins Constituting Myofibrils in Living Muscle Cells

    Shimada, Yutaka (et al.)

    Pages 21-39

  • Emergence of the First Myofibrils and Targeting Mechanisms Directing Sarcomere Assembly in Developing Cardiomyocytes

    Ehler, Elisabeth (et al.)

    Pages 41-58

  • Tropomodulin: An Important Player in Cardiac Myofibrillogenesis

    McLellan, Catherine (et al.)

    Pages 59-69

  • Maintaining the Fully Differentiated Cardiac Sarcomere

    Michele, Daniel E. (et al.)

    Pages 73-85

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-4612-0199-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-0-8176-4226-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-1-4612-6658-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Myofibrillogenesis
Editors
  • Dipak K. Dube
Series Title
Cardiovascular Molecular Morphogenesis
Copyright
2002
Publisher
Birkhäuser Basel
Copyright Holder
Birkhäuser Boston
eBook ISBN
978-1-4612-0199-1
DOI
10.1007/978-1-4612-0199-1
Hardcover ISBN
978-0-8176-4226-6
Softcover ISBN
978-1-4612-6658-7
Edition Number
1
Number of Pages
XVI, 270
Topics