Endocrine Updates

RNA Binding Proteins

New Concepts in Gene Regulation

Editors: Sandberg, Kathryn, Mulroney, Susan E. (Eds.)

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About this book

RNA binding proteins are an exciting area of research in gene regulation. A multitude of RNA-protein interactions are used to regulate gene expression including pre-mRNA splicing, polyadenylation, editing, transport, cytoplasmic targeting, translation and mRNA turnover. In addition to these post-transcriptional processes, RNA-protein interactions play a key role in transcription as illustrated by the life cycle of retroviruses. Unlike DNA, the structure of RNA is highly variable and conformationally flexible, thus creating a number of unique binding sites and the potential for complex regulation by RNA binding proteins.
Although there is a wide range of topics included in this volume, general themes have been repeated, highlighting the overall integrative nature of RNA binding proteins. The chapters have been separated into three different sections: Translational Control; mRNA Metabolism; and Hormonal and Homeostatic Regulation. The chapters of this volume were written with the seasoned investigator and student in mind. Summaries of key concepts are reviewed within each chapter as well as guiding questions that can be used to stimulate class discussions. The Editors of this volume hope that this compendium educates, enthralls, and stimulates the readers to look to the future possibilities in this rapidly evolving field.

Table of contents (17 chapters)

  • The Role of RNA-Binding Proteins in IRES-Dependent Translation

    Jang, Sung Key (et al.)

    Pages 1-33

  • Translational Regulation of Masked Maternal mRNAs in Early Development

    Standart, Nancy

    Pages 35-51

  • Poly-C Binding Proteins: Cellular Regulators of mRNA Fate and Function

    Gamarnik, Andrea V. (et al.)

    Pages 53-69

  • Autoregulation of Protein Synthesis by Translation

    Kwon, Guim (et al.)

    Pages 71-86

  • Translational Initiation of Ornithine Decarboxylase mRNA

    Persson, Lo (et al.)

    Pages 87-100

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4757-6446-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-0-7923-7612-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4419-4935-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
RNA Binding Proteins
Book Subtitle
New Concepts in Gene Regulation
Editors
  • Kathryn Sandberg
  • Susan E. Mulroney
Series Title
Endocrine Updates
Series Volume
16
Copyright
2002
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4757-6446-8
DOI
10.1007/978-1-4757-6446-8
Hardcover ISBN
978-0-7923-7612-5
Softcover ISBN
978-1-4419-4935-6
Series ISSN
1566-0729
Edition Number
1
Number of Pages
XVI, 308
Topics