The African Trypanosomes

1. Front Matter

   Pages i-ix

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2. African Trypanosomiasis: Failure of Science and Public Health

   • D. H. Molyneux

   Pages 1-10

3. The Programme Against African Trypanosomiasis Information System (Paatis)

   • M. Gilbert, C. Jenner, J. Pender, D. Rogers, J. Slingenbergh, W. Wint

   Pages 11-24

4. Effects of Climate, Human Population and Socio-economic Changes on Tsetse-transmitted Trypanosomiasis to 2050

   • J.J. McDermott, P.M. Kristjanson, R.L. Kruska, R.S. Reid, T.P. Robinson, P.G. Coleman et al.

   Pages 25-38

5. Tsetse Vector Based Strategies for Control of African Try Panosomiasis

   • S. Aksoy

   Pages 39-49

6. Diagnosis of Human and Animal African Trypanosomiasis

   • P. Büscher

   Pages 51-63

7. Chemotherapy of African Trypanosomiasis

   • John Richard Seed, David W. Boykin

   Pages 65-78

8. Immunobiology of African Trypanosomiasis: New Paradigms, Newer Questions

   • John M. Mansfield, Tinsley H. Davis, Melissa E. Dubois

   Pages 79-96

9. Identifying the Mechanisms of Trypanotolerance in Cattle

   • J. Naessens, D.J. Grab, M. Sileghem

   Pages 97-111

10. Trypanosome Factors Controlling Population Size and Differentiation Status

    • N.B. Murphy, T. Olijhoek

    Pages 113-126

11. Endocytosis in African Trypanosomes

    • Derek P. Nolan, Jose A. Garcia-Salcedo, Maurice Geuskens, Didier Salmon, Françoise Paturiaux-Hanocq, Annette Pays et al.

    Pages 127-141

12. The Genome of the African Trypanosome

    • John E. Donelson

    Pages 143-158

13. Towards a Trypanosomiasis Vaccine

    • Samuel J. Black, Noel B. Murphy, Derek P. Nolan

    Pages 159-174

14. Back Matter

    Pages 175-179

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African trypanosomes are tsetse-transmitted protozoa that inhabit the extracellular compartment of host blood. They cause fatal sleeping sickness in people, and Nagana, a wasting and generally fatal disease, in cattle. While trypanosomes are most common to Africa (about 30% of Africa's cattle graze on the fringe of the tsetse habitat), some species have spread beyond its boarders to Asia, the Middle East and South America.
The African Trypanosomes, volume one of World Class Parasites, is written for researchers, students and scholars who enjoy reading research that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. It is intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. It integrates vector, pathogen and host biology and celebrates the diversity of approach that comprises modern parasitological research.

• biology
• morphology
• parasite
• parasites
• protozoa
• system
• taxonomy
• vaccine

'[...] this book is not just attractive for researchers working on African trypanosomiasis, it will also be a very useful addition to the protozoological section of a library for other researchers and students.'
European Journal of Protistology, 38 (2002)

• Environment Dept. Veterinary & Animal Sciences, University of Massachusetts College of Natural Resources & the, Amherst, USA

  Samuel J. Black

• Dept. Epidemiology Div. Infectious Diseases, University of North Carolina School of Public Health, Chapel Hill, USA

  J. Richard Seed

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