Cancer Treatment and Research

Myelodysplastic Syndromes & Secondary Acute Myelogenous Leukemia

Directions for the New Millennium

Editors: Raza, Azra, Mundle, Suneel D. (Eds.)

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About this book

Myelodysplastic syndromes are to the bone marrow what pneumonia is to the lungs; the response of an organ to a variety of etiologic insults like aging, toxic exposure, infections and auto-immunity. Among infectious causes alone, pneumonia could be the result of a variety of possible pathogens including bacterial, viral, tuberculous or fungal agents. Similarly, MDS cannot be treated as a single disease. Attempts to harness the inherent complexity of MDS by devising `classifications' which group the various syndromes as one disease is as misguided as saying that a pneumonia is not infectious because it did not respond to antibiotics. Progress in the field will occur faster when we re-analyze this premise. Therefore, until a clearer picture of the disease emerges it is best to treat each of the MDS syndromes as a separate entity. Having no classification is better than a misleading one.
Cancer research has been notable for its periodic cycles of promise and hope, followed by defeat and disappointments. It is not that there is no solution, but that the problem has not been identified precisely. This book is our attempt to define the most crucial questions related to MDS that need to be addressed immediately through logic, analysis and rigorous experimentation. If the emerging problems appear daunting, then instead of being overwhelmed by them, we should follow the advice of the great 20th century thinker Antonio Gramsci, `pessimism of the intellect must be faced with the optimism of will'.

Table of contents (14 chapters)

  • Evolving Concepts in Myelodysplastic Syndromes

    Raza, Azra

    Pages 1-24

  • In Vitro Biology of the Hematopoietic System in Myelodysplastic Syndromes

    Mayani, Hector

    Pages 25-43

  • Biology of Stem and Myeloid Progenitor Cells in Myelodysplastic Syndromes

    Span, Lambert F. R. (et al.)

    Pages 45-63

  • Novel in Vitro Culture and Ultrastructural Techniques to Study the Biology of Myelodysplastic Syndromes (MDS)

    Alvi, Sairah (et al.)

    Pages 65-79

  • The Monocytic Component in Myelodysplastic Syndromes

    Castoldi, Gianluigi (et al.)

    Pages 81-92

Buy this book

eBook $239.00
price for USA (gross)
  • ISBN 978-1-4615-1463-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $309.00
price for USA
  • ISBN 978-0-7923-7396-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $309.00
price for USA
  • ISBN 978-1-4613-5566-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Myelodysplastic Syndromes & Secondary Acute Myelogenous Leukemia
Book Subtitle
Directions for the New Millennium
Editors
  • Azra Raza
  • Suneel D. Mundle
Series Title
Cancer Treatment and Research
Series Volume
108
Copyright
2001
Publisher
Springer US
Copyright Holder
Kluwer Academic Publishers
eBook ISBN
978-1-4615-1463-3
DOI
10.1007/978-1-4615-1463-3
Hardcover ISBN
978-0-7923-7396-4
Softcover ISBN
978-1-4613-5566-3
Series ISSN
0927-3042
Edition Number
1
Number of Pages
XIV, 280
Topics