Cardiac Allograft Rejection

Editors: Dec, G.W., Narula, J., Ballester, M., Carrio, I. (Eds.)

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About this book

Heart transplantation remains one of the major scientific achievements of twentieth century medicine. During the past four decades, it has evolved from an unproven experimental surgical technique to the most effective form of therapy for refractory end-stage heart disease. It has captured the public's imagination and expanded our understanding of fundamental immunologic mechanisms that are responsible for cellular and humorally-mediated immunity. Despite its successes, many clinical and scientific problems remain. One or more bouts of acute cellular or humoral (vascular) rejection will occur in over 75% of transplant recipients despite current immunosuppressive strategies. Further, rejection directly results in approximately 20% of post-transplant deaths and is believed to play a major role in the development of late allograft dysfunction and coronary vasculopathy.
This book by international experts in the fields of transplantation medicine, immunobiology and cardiac imaging provides the reader with an up-to-date, consise summary of the latest developments in the diagnosis and treatment of acute cardiac rejection. It is axiomatic that a more complete understanding of the pathogenic processes involved in rejection will ultimately lead to its prevention. This volume will be useful to transplant cardiologists, cardiovascular surgeons, cardiac pathologists and transplant scientists who seek to prolong the lifespan and improve the quality of life of their transplant recipients.

Table of contents (20 chapters)

  • Histocompatibility Antigens and Transplant Rejection

    Pillai, Shiv

    Pages 3-20

  • Immunology of Cellular and Humoral Rejection after Cardiac Transplantation

    Rose, Marlene L. (et al.)

    Pages 21-47

  • Immunobiology of Chronic Cardiac Allograft Rejection

    Koskinen, Petri (et al.)

    Pages 49-64

  • Inflammatory Cell Infiltration, Cytokines, and Mechanisms of Myocyte Necrosis in Cardiac Transplant Rejection

    Sundstrom, Jay Bruce (et al.)

    Pages 65-88

  • Apoptosis in Cardiac Transplant Rejection

    Puig, Mireia (et al.)

    Pages 89-100

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4615-1649-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-0-7923-7329-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4613-5659-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cardiac Allograft Rejection
Editors
  • G. William Dec
  • Jagat Narula
  • Manel Ballester
  • Ignasi Carrio
Copyright
2001
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-1649-1
DOI
10.1007/978-1-4615-1649-1
Hardcover ISBN
978-0-7923-7329-2
Softcover ISBN
978-1-4613-5659-2
Edition Number
1
Number of Pages
XVII, 434
Topics