Endocrine Updates

Prolactin

Editors: Horseman, Nelson D. (Ed.)

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Hardcover $329.00
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About this book

It is an authentic privilege to have the opportunity to assemble and edit a new volume on "Prolactin," the first in several decades to be devoted to this fascinating hormone in all its aspects. The obvious clinical rationale for understanding prolactin (PRL) is the frequent occurrence of prolactinomas, the most common type of pituitary tumor. Fortunately, medical management of prolactinomas can be based on our under­ standing of the physiology of hypothalamic control of the lactotroph. Armed with this knowledge, therapies for proiactinomas are highly successful and well tolerated. Be­ cause of the historical and practical importance of knowledge regarding the hypothala­ mus-Iactotroph axis, the first chapters of this volume are dedicated to reviewing the physiology, development, and cell biology of lactotroph regulation. Chapters focusing on prolactinomas and related clinical issues follow these. PRL is the primary hormone that is responsible for "parental care" in many verte­ brate species. This reproductive strategy is not unique to mammals, but it has devel­ oped through evolution to be the central distinguishing feature of the mammalian life cycle. Among the mammals, mice have become the most effective research species in recent years. This can be traced to the development of a wide range of methods for manipulating mouse genetics, and thereby influencing development, physiology and behavior. Mice also provide a profound illustration of the physiological challenges faced in maternity. Female mice undergo a post-partum estrous, and often are both pregnant and lactating simultaneously.

Table of contents (19 chapters)

  • Hypothalamic Control of Prolactin Synthesis and Secretion

    Ben-Jonathan, Nira

    Pages 1-24

  • Role of Prolactin in Developmental Differentiation of Hypothalamic Dopaminergic Neurons

    Phelps, Carol J. (et al.)

    Pages 25-43

  • Mechanisms of Dopamine Action on the Lactotroph

    Gregerson, Karen A.

    Pages 45-61

  • Regulation of Lactotrophs and Prolactin Secretion in Non-mammalian Vertebrates

    Porter, Tom E. (et al.)

    Pages 63-79

  • Prolactinomas

    Molitch, Mark E.

    Pages 81-99

Buy this book

eBook $259.00
price for USA (gross)
  • ISBN 978-1-4615-1683-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $329.00
price for USA
  • ISBN 978-0-7923-7290-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $329.00
price for USA
  • ISBN 978-1-4613-5676-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Prolactin
Editors
  • Nelson D. Horseman
Series Title
Endocrine Updates
Series Volume
12
Copyright
2001
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-1683-5
DOI
10.1007/978-1-4615-1683-5
Hardcover ISBN
978-0-7923-7290-5
Softcover ISBN
978-1-4613-5676-9
Series ISSN
1566-0729
Edition Number
1
Number of Pages
VII, 412
Topics