Endocrine Updates

Genetics of Diabetes Mellitus

Editors: Lowe Jr., William L. (Ed.)

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Hardcover $289.00
price for USA
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Softcover $289.00
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About this book

Genetics of Diabetes Mellitus is intended to be a resource for both researchers in the field as well as endocrinologists, diabetologists, and geneticists who seek to learn more about this rapidly changing and important field. The text contains chapters from experts in the area who review aspects of the genetics of both type 1 and 2 diabetes mellitus as well as various syndromic forms of diabetes. The chapters are approachable for those who are not experts in the field of genetics but also comprehensive, so as to serve as an important resource for researchers interested in the genetics of diabetes mellitus.
A description of basic concepts of the genetics of complex diseases like type 1 and type 2 diabetes is provided as background. Type 1 diabetes is addressed in chapters exploring genetic determinants that affect the autoimmune process characteristic of type 1 diabetes, the role of the insulin gene in the pathogenesis of type 1 diabetes and additional genes that may impact upon the risk of type 1 diabetes. The impact of genetic determinants on the pathophysiology of type 2 diabetes is covered, as are chapters that address specific genes that are important for the development of type 2 diabetes. Finally, syndromic forms of diabetes, including Maturity Onset Diabetes of the Young and mitochondrial diabetes, and the insight that these disorders provide into more common forms of diabetes are reviewed.
Thus, this comprehensive and up-to-date text will serve as an important resource for those actively engaged in research in this area and clinicians treating these patients to provide an up-to-date entrée for those seeking to become more knowledgeable in the area.

Table of contents (11 chapters)

  • Genetics of Complex Diseases

    Nye, Steven H. (et al.)

    Pages 1-23

  • Genetic Factors in Type 1 Diabetes

    Pugliese, Alberto

    Pages 25-42

  • Type 1 Diabetes, Autoimmunity, and the MHC

    Fain, Pamela R. (et al.)

    Pages 43-64

  • The Insulin VNTR in the Genetics of Type 1 Diabetes

    Polychronakos, Constantin (et al.)

    Pages 65-77

  • Maturity Onset Diabetes of the Young (Mody)

    Froguel, Philippe (et al.)

    Pages 79-89

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4615-1597-5
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-0-7923-7252-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4613-5633-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Genetics of Diabetes Mellitus
Editors
  • William L. Lowe Jr.
Series Title
Endocrine Updates
Series Volume
10
Copyright
2001
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4615-1597-5
DOI
10.1007/978-1-4615-1597-5
Hardcover ISBN
978-0-7923-7252-3
Softcover ISBN
978-1-4613-5633-2
Series ISSN
1566-0729
Edition Number
1
Number of Pages
VIII, 255
Topics