Human Cell Culture

Cancer Cell Lines Part 2

Editors: Masters, John, Palsson, Bernhard Ø (Eds.)

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eBook $229.00
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  • ISBN 978-0-306-46861-2
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About this book

Continuous cell lines derived from human cancers are the mostwidely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions offundamental importance to the relevanceof human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation? 2. Do the cell lines accurately represent the histopathology of the original tumors? 3. Do the cell lines accurately represent the molecular genetics of this type of cancer? The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative oftumors at that site is naïve and misleading.

Table of contents (18 chapters)

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-0-306-46861-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-0-7923-5878-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-90-481-5286-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cancer Cell Lines Part 2
Editors
  • John Masters
  • Bernhard Ø Palsson
Series Title
Human Cell Culture
Series Volume
2
Copyright
2002
Publisher
Springer Netherlands
Copyright Holder
Springer Science+Business Media Dordrecht
eBook ISBN
978-0-306-46861-2
DOI
10.1007/0-306-46861-1
Hardcover ISBN
978-0-7923-5878-7
Softcover ISBN
978-90-481-5286-5
Series ISSN
1389-2142
Edition Number
1
Number of Pages
X, 377
Topics