Peptides

1. Front Matter

   Pages i-lxii

   PDF

2. First Merrifield Award Lecture-Makineni Lecture

   1. Fifty years of my protein synthesis

      • Shumpei Sakakibara

      Pages 1-9

3. Keynote Lecture

   1. “The time has come,” the Walrus said, “to talk of many things...” -Lewis Carroll, Through the Looking Glass

      • Ralph Hirschmann

      Pages 11-16

4. Peptide Diversity and Chemical Libraries

   1. Novel concepts for the synthesis of cyclic peptide libraries

      • Lianshan Zhang, James P. Tam

      Pages 19-21

   2. Combinatorics, peptide mimetics, and combizymes

      • Hyunsoo Han, Anthony M. Vandersteen, Kim D. Janda

      Pages 22-24

   3. Peptides as precursors in the synthesis of heterocyclic positional scanning combinatorial libraries

      • Jean-Philippe Meyer, John M. Ostresh, Adel Nefzi, Vince T. Hamashin, Christa C. Schoner, Marc A. Giulianotti et al.

      Pages 25-27

   4. Expanding molecular diversity with pseudopeptides and macrotorials: Synthesis, characterization, and biological activities of macrocyclic combinatorial libraries

      • Arno F. Spatola, Yvon Crozet, Peteris Romanovskis, David Vogel

      Pages 28-30

   5. Solid phase synthesis of peptidomimetics

      • J. P. Mayer, D. Bankaitis-Davis, G. Beaton, K. Bjergarde, J. J. Gaudino, B. A. Goodman et al.

      Pages 31-33

   6. Determination of the amino acid composition of the bioactive components in peptide libraries

      • Árpád Furka, Eugen Câmpian, Hans R. Tanner, Hossain H. Saneii

      Pages 34-36

   7. Backbone amide linker (BAL) for solid-phase synthesis of 2,5-piperazinediones (DKP), useful scaffolds for combinatorial chemistry

      • Fernando Albericio, Montse del Fresno, Ariadna Frieden, Miriam Royo, Jordi Alsina, Knud J. Jensen et al.

      Pages 37-39

   8. Fluorescent quenched substrates for protein disulfide isomerase (PDI) defined by the use of disulfide bridge containing libraries

      • J. C. Spetzer, V. Westphal, J.R. Winther, M. Meldal

      Pages 40-41

   9. Solid phase synthesis of cyclic homodetic peptide libraries utilizing a novel intraresin chain transfer

      • Michael L. Moore, Kenneth A. Newlander, Heidemarie Bryan, William M. Bryan, William F. Huffman

      Pages 42-44

   10. Analysis of O-and N-linked glycopeptide libraries by MALDI-TOF MS: Application in solid phase assays of carbohydrate-binding-proteins

       • Phaedria M. St. Hilaire, Morten Meldal, Klaus Bock

       Pages 45-46

   11. Unsymmetrically functionalized polyamine libraries by a solid phase strategy starting from their symmetrical polyamine-counterparts

       • Gerardo Byk, Marc Frederic, Daniel Scherman

       Pages 47-48

   12. Development of DNA-encoded library containing 109backbone cyclic peptides on 7 µm glass beads

       • Anna Balanov, Eran Hadas, Ilana Cohen

       Pages 49-50

   13. Introduction of bulky betidamino acids in thyrotropin releasing hormone (TRH)

       • Dean A. Kirby, Marvin C. Gershengorn, Jean E. River

       Pages 51-52

   14. Combinatorial libraries and polyamines in the battle against Third World trypanosomes

       • Helen K. Smith, Mark Bradley

       Pages 53-54

   15. Hybrid resins for synthesis and screening of synthetic peptide libraries

       • Hoebert S. Hiemstra, Willemien E. Benckhuijsen, Wolfgang E. Rapp, Jan W. Drijfhout

       Pages 55-56

   16. Combinatorial libraries: Equimolar incorporation of benzaldehyde mixtures in reductive alkylation reactions

       • John M. Ostresh, Christa C. Schoner, Marc A. Giulianotti, Michael J. Kurth, Barbara Dörner, Richard A. Houghten

       Pages 57-58

   17. Potential cancer vaccine: Anti-idiotype antibodies developed from antigen binding peptides bind to human breast cancer antigen

       • John Mark Carter, Judy Singleton, Phoebe Strome, Cindy Coleman, Vernon Alvarez

       Pages 59-60

The Fifteen American Peptide Symposium (15APS) was held in Nashville, Tennessee, on June 14-19, 1997. This biennial meeting was jointly sponsored by the American Peptide Society and Vanderbilt University. The attendance of 1,081 participants from 37 countries was lower than the two previously held Symposia. However, the number of participating countries was the largest. Thus, it was gratifying to see that this meeting retained both its international flavor and participant loyalty at a time when there are many more symposia held each year on similar subjects. The scientific program, thanks to the insights and efforts of the Program Committee as well as Dr. Peter Schiller, the President of the American Peptide Society, was extraordinarily rich, diverse, and exciting. It was comprised of 124 oral and 550 poster presentations. Three prominent format changes were installed. First, the Symposium started on Saturday instead of Sunday. Second, the program opened on Saturday afternoon with a Mini-symposium by the Young Investigators to give them an early start and attention. Finally, 40 short and definitive reports were given in two parallel sessions. The expanded format permitted an unprecedented number of lectures and enabled wider participation by the attending delegates.

• Vakuuminjektionsverfahren
• biology
• protein
• receptor

• Department of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, USA

  James P. Tam

• Departments of Ob/Gyn, Medical Biochemistry and Microbiology and The Comprehensive Cancer Center, The Ohio State University, Columbus, USA

  Pravin T. P. Kaumaya

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