Developments in Oncology

Basic and Clinical Applications of Flow Cytometry

Proceeding of the 24th Annual Detroit Cancer Symposium Detroit, Michigan, USA - April 30, May 1 and 2, 1992

Editors: Valeriote, Frederick A., Nakeff, Alexander, Valdivieso, Manuel (Eds.)

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About this book

The focus of this symposium was on the present and future capabilities of flow cytometry for both medical and biological applications in cancer. This technology began with quite modest instrumentation, with limited capabilities to answer biological questions. Today, both the clinical workhorses and the powerful multi-laser, multi-detector, sorting machinery, coupled with sophisticated computers and storage devices and the increasing storehouse of markers and dyes, are taking us to the limit and beyond in finding answers to the cause and cure of cancer.
In the past, both normal hematopoietic tissue and leukemias have been the tissue samples of choice in the application of flow cytometry, and some of the most recent applications with these tissues are presented here. However, the book also discusses the increasingly sophisticated disaggregation techniques which allow investigators the possibility to train their lasers on solid tumors. Not only can we use flow cytometry with associated fluorescent markers to understand the biology of cancer, but also the wide array of existing and developing markers provides us with important diagnostic tools in the detection of cancer early in either the malignant or relapse process. And the field comes full circle, with the use of the technology for gene mapping and other genetic studies to unlock the basic malignant process.

Table of contents (18 chapters)

  • Cytometry 2000: Laser Probing the Future

    Nakeff, Alexander

    Pages 1-3

  • Activation and Proliferation of Purified Hematopoietic Precursor Cells from Human Bone Marrow

    Lansdorp, P. (et al.)

    Pages 5-12

  • Flow Cytometric Proliferative Fraction Analysis in Solid Tumors

    Visscher, Daniel W. (et al.)

    Pages 13-32

  • Mitogenic and Non-Mitogenic Induction of Lymphocytic Invasion: Dual Parameter flow Cytometric Analysis

    Ratner, S. (et al.)

    Pages 33-47

  • Flow Cytometric Monitoring of Drug Resistance in Human Solid Tumors

    Krishan, Awtar (et al.)

    Pages 49-64

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-1-4613-1253-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $319.00
price for USA
  • ISBN 978-0-7923-3809-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-1-4612-8534-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Basic and Clinical Applications of Flow Cytometry
Book Subtitle
Proceeding of the 24th Annual Detroit Cancer Symposium Detroit, Michigan, USA - April 30, May 1 and 2, 1992
Editors
  • Frederick A. Valeriote
  • Alexander Nakeff
  • Manuel Valdivieso
Series Title
Developments in Oncology
Series Volume
77
Copyright
1996
Publisher
Springer US
Copyright Holder
Kluwer Academic Publishers
eBook ISBN
978-1-4613-1253-6
DOI
10.1007/978-1-4613-1253-6
Hardcover ISBN
978-0-7923-3809-3
Softcover ISBN
978-1-4612-8534-2
Edition Number
1
Number of Pages
XII, 318
Topics