Developments in Nuclear Medicine

Clinical Application of Radiolabelled Platelets

Editors: Kessler, C., Hardeman, M., Henningsen, H., Petrovici, J. (Eds.)

Buy this book

eBook $69.99 net
( price for USA )
  • ISBN 978-94-009-0581-8
  • digitally watermarked, no DRM
  • included format: PDF
  • eBooks can be used on all Reading Devices
Hardcover $99.00 net
( price for USA )
  • ISBN 978-0-7923-0729-7
  • free shipping for individuals worldwide
  • The book title is in reprint. You can already preorder it.
Softcover $99.00 net
( price for USA )
  • ISBN 978-94-010-6749-2
  • free shipping for individuals worldwide
  • usually dispatched within 3 to 5 business days
About this book

AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.

Free Preview

Buy this book

eBook $69.99 net
( price for USA )
  • ISBN 978-94-009-0581-8
  • digitally watermarked, no DRM
  • included format: PDF
  • eBooks can be used on all Reading Devices
Hardcover $99.00 net
( price for USA )
  • ISBN 978-0-7923-0729-7
  • free shipping for individuals worldwide
  • The book title is in reprint. You can already preorder it.
Softcover $99.00 net
( price for USA )
  • ISBN 978-94-010-6749-2
  • free shipping for individuals worldwide
  • usually dispatched within 3 to 5 business days

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Clinical Application of Radiolabelled Platelets
Series Title
Developments in Nuclear Medicine
Series Volume
17
Copyright
1990
Publisher
Springer Netherlands
Copyright Holder
Kluwer Academic Publishers
eBook ISBN
978-94-009-0581-8
DOI
10.1007/978-94-009-0581-8
Hardcover ISBN
978-0-7923-0729-7
Softcover ISBN
978-94-010-6749-2
Edition Number
1
Topics