Mitochondria and Cancer

Editors: Singh, Keshav, Costello, Leslie (Eds.)

  • Aims to provide a comprehensive analysis of the role mitochondria play in carcinogenesis
  • Will also provide up to date mitochondrial therapeutic approaches for treatment of cancer
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Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-0-387-84835-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-0-387-84834-1
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
Softcover $199.00
price for USA
  • ISBN 978-1-4419-2738-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Nearly a century of scientific research has revealed that mitochondrial dysfunction is one of the most common and consistent phenotypes of cancer cells. A number of notable differences in the mitochondria of normal and cancer cells have been described. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins. This book, Mitochondria and Cancer, edited by Keshav K. Singh and Leslie C. Costello, presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy.

Table of contents (14 chapters)

  • Integration of Genetic, Proteomic, and Metabolic Approaches in Tumor Cell Metabolism

    Costello, Leslie C. (et al.)

    Pages 1-14

  • Mitochondria and Cancer

    Owens, Kjerstin M. (et al.)

    Pages 1-21

  • Warburg and his Legacy

    Ristow, Michael (et al.)

    Pages 23-38

  • The Lipogenic Switch in Cancer

    Brusselmans, Koen (et al.)

    Pages 39-59

  • Citrate Metabolism in Prostate and Other Cancers

    Franklin, Renty B. (et al.)

    Pages 61-78

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-0-387-84835-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-0-387-84834-1
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
Softcover $199.00
price for USA
  • ISBN 978-1-4419-2738-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Mitochondria and Cancer
Editors
  • Keshav Singh
  • Leslie Costello
Copyright
2009
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-0-387-84835-8
DOI
10.1007/978-0-387-84835-8
Hardcover ISBN
978-0-387-84834-1
Softcover ISBN
978-1-4419-2738-5
Edition Number
1
Number of Pages
XII, 289
Number of Illustrations and Tables
39 b/w illustrations, 7 illustrations in colour
Topics