Reelin Glycoprotein

Structure, Biology and Roles in Health and Disease

Editors: Fatemi, S.H. (Ed.)

  • Provides an unprecedented analysis of this emerging and novel protein by examining evidence from genetic, neuroanatomic, biochemical, and behavioral studies
  • A comprehensive and integrative book
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eBook $219.00
price for USA (gross)
  • ISBN 978-0-387-76761-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-0-387-76760-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-1-4899-8695-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Reelin glycoprotein is a major secretory protein with important roles in embryogenesis and during adult life. Reelin gene mutations or deficiency of the protein product cause abnormal cortical development and reelin signaling impairment in brain. Since the first discovery of the reelin mutant mouse in 1951 by Falconer, and later discovery of the gene for reelin in 1995, there has been an explosion of new knowledge about this important molecule. Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease, written by an international panel of experts, summarizes the state of the knowledge on various aspects of reelin. Topics include the reelin gene and its receptors, downstream effector molecules in reelin signaling cascade, chemistry and structure of reelin, comparative anatomy of reelin, presence of reelin in various body tissues, reelin mutations, and abnormalities of reelin production in neuropsychiatric disorders and cancer. This book will serve as a foundation for analysis of this emerging novel protein for all neuroscientists and clinicians.

Reviews

From the reviews:

"The glycoprotein reelin, involved in a multitude of important neurobiological processes including embryogenesis and brain development, is the focus of this informative and interesting book. … The intended audience includes researchers in the field and clinicians. Clinicians who are interested in understanding the importance of epigenetic factors involved in neuropsychiatric disorders would be find this book helpful. … This is an excellent summary of the current state of research findings on this putatively important glycoprotein." (Michael J. Schrift, Doody’s Review Service, July, 2009)

“The whole book is dedicated just to one biopolymer, reelin, which is a major secretory glycoprotein with biological activity in various processes of our body. … The book consists of 28 chapters presented by international group of experts. … book will be very useful as foundation for analysis of this emerging novel glycoprotein for biochemists, molecular biologists, neuroscientists, and clinicians specialized in psychiatric disorders.” (G. Ya. Wiederschain, Biochemistry, Vol. 75 (5), 2010)

Table of contents (28 chapters)

  • The Reelin Gene and Its Functions in Brain Development

    Huang, Cheng-Chiu (et al.)

    Pages 1-13

  • Apolipoprotein E Receptor 2 and Very-Low-Density Lipoprotein Receptor: An Overview

    Bock, Hans H. (et al.)

    Pages 15-35

  • Chemistry of Reelin

    Jossin, Yves

    Pages 37-47

  • The C-Terminal Region of Reelin: Structure and Function

    Hattori, Mitsuharu

    Pages 49-56

  • Crystal Structure of Reelin Repeats

    Takagi, Junichi

    Pages 57-67

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-0-387-76761-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-0-387-76760-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-1-4899-8695-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Reelin Glycoprotein
Book Subtitle
Structure, Biology and Roles in Health and Disease
Editors
  • S.H. Fatemi
Copyright
2008
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-0-387-76761-1
DOI
10.1007/978-0-387-76761-1
Hardcover ISBN
978-0-387-76760-4
Softcover ISBN
978-1-4899-8695-5
Edition Number
1
Number of Pages
XXIII, 443
Topics