Cannabinoids and the Brain

Editors: Köfalvi, Attila (Ed.)

  • Explores the neuroscience and therapeutic potential of cannabinoids in great detail
  • Presents the latest research in the growing endocannabinoid research field
  • Sets forth a current understanding of the neurobiology of endocannabinoids and related systems, detailing their pathophysiological role and therapeutic potential
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eBook $189.00
price for USA (gross)
  • ISBN 978-0-387-74349-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
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  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-0-387-74348-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4419-4493-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

In the last 15 years, a particular lipid messenger system has been discovered to be a guard and shaper of the life and activity of most human cell types from cradle to grave. Taking the nervous tissue as an example: the artistically complex endocannabinoid system provides promising therapeutic targets in cancer, epilepsy, multiple sclerosis, Alzheimer's or Parkinson's diseases, inflammation, pain, schizophrenia, depression, and anxiety. Nevertheless, it is a little embarrassing that the word 'cannabinoid' still evokes the image of the hippies or hashish as the first associations not only in everyday people but in medical, scientific and legal professionals, respectively.

 Cannabinoids and the Brain is a timely compilation of thorough reviews, written by the world’s leading neuroscience and clinical authors, covering the latest information concerning basic and clinical neuroscience of the endocannabinoid and related messenger systems. As Rimonabant™, the first intentionally cannabinoid receptor-targeted medicine has been marketed in Europe since 2006, the authors consider it particularly important to include the central and peripheral pathomechanisms of metabolic disorders in the present volume.

Cannabinoids and the Brain gives a comprehensive overview of all the essential literature concerning the endocannabinoid and related systems in the nervous tissue. It is a rapidly expanding research field and the widespread presence of cannabinoids in most physiopathological mechanisms appear to hinder the effort to fully cover the subject. By the end of the book, the reader will have a solid knowledge of the genetics, molecular biology, anatomy, pharmacology, and physiology of the endocannabinoid system and its involvement in neurological and psychiatric disorders, and will eventually discover a natural relationship among marijuana, aspirin, and chili pepper. 

Table of contents (10 chapters)

  • CB1 Cannabinoid Receptors: Molecular Biology, Second Messenger Coupling and Polarized Trafficking in Neurons

    Andrew J. Irving, Neil A. McDonald, Tibor Harkany

    Pages 59-73

  • CB1 and CB2 Receptor Pharmacology

    Roger G. Pertwee

    Pages 91-99

  • Alternative Interacting Sites and Novel Receptors for Cannabinoid Ligands

    Attila Köfalvi

    Pages 131-160

  • Anatomical Distribution of Receptors, Ligands and Enzymes in the Brain and in the Spinal Cord: Circuitries and Neurochemistry

    Giovanni Marsicano, Rohini Kuner

    Pages 161-201

  • Endocannabinoids at the Synapse: Retrograde Signaling and Presynaptic Plasticity in the Brain

    Gregory L. Gerdeman

    Pages 203-236

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-0-387-74349-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-0-387-74348-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4419-4493-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cannabinoids and the Brain
Editors
  • Attila Köfalvi
Copyright
2008
Publisher
Springer US
Copyright Holder
Springer-Verlag US
eBook ISBN
978-0-387-74349-3
DOI
10.1007/978-0-387-74349-3
Hardcover ISBN
978-0-387-74348-6
Softcover ISBN
978-1-4419-4493-1
Edition Number
1
Number of Pages
XV, 583
Topics