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Functional Nucleic Acids for Analytical Applications

  • Book
  • © 2009

Overview

  • First in the rapidly emerging field on analytical applications for nucleic acids
  • With interdisciplinary approach, a valuable tool for researchers in chemistry, biology, and engineering
  • One of the first books in the series Integrated Microanalytical Systems, recently renamed Integrated Analytical Systems, edited by R. Potyrailo

Part of the book series: Integrated Analytical Systems (ANASYS)

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Table of contents (15 chapters)

  1. Overview of Functional Nucleic Acids and Their Analytical Applications

  2. Functional Nucleic Acid Sensors Based on Different Transduction Principles

  3. Other Emerging Analytical Applications

Keywords

About this book

Nature has long used nucleic acid aptamers and enzymes for regulatory activities, such as the recently discovered “riboswitches” involved in gene expression. The existence of a large array of natural and artificial functional nucleic acids has generated tremendous enthusiasm and new opportunities for molecular scientists from diverse disciplines to devise new concepts and real applications that take advantage of those nucleic acids for sensing and other analytical applications. This book provides a timely and comprehensive overview of recent advances in the field, from leading experts in biology, chemistry, and engineering. A variety of topics are covered, from fundamentals of functional nucleic acids, to their applications as sensors, to nanotechnologies; as well as integration of functional nucleic acids into practical analytical systems.

Reviews

From the reviews:

"This book consists of 15 chapters contributed by experts in the field of functional nucleic acids, mostly in the area of specific analytical applications of nucleic acids … . this book affords a comprehensive collection of clearly presented, up-to-date reviews that broadly cover the numerous applications of functional nucleic acids. … The chapters are of high quality … that will be useful to newcomers entering the field of functional nucleic acids and to those interested in exploring other applications complementary to their own niches." (Jennifer S. Brodbelt, Journal of the American Chemical Society, Vol. 131 (32), 2009)

“The book is well structured and combines 15 insightful reviews written by many leading experts. … Functional Nucleic Acids for Analytical Applications is a comprehensive and well written book. With its excellent review of recent progress and critical outlook of future directions it will be very valuable for researchers wishing to explore the unique properties of FNAs for different applications in analytical and bioanalytical chemistry.”­­­ (Xiaohong Fang, Analytical and Bioanalytical Chemistry, Vol. 398, June, 2010)

Editors and Affiliations

  • Department of Biochemistry and Biomedical Sciences, McMaster University Hamilton, Ontario, Canada

    Li Yingfu

  • Department of Chemistry, University of Illinois at Urbana-Champaign Urbana, Illinois, USA

    Lu Yi

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