Medical Intelligence Unit

Mechanisms of Insulin Action

Editors: Saltiel, Alan R., Pessin, Jeffrey E. (Eds.)

  • Attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states

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eBook $229.00
price for USA (gross)
  • ISBN 978-0-387-72204-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-0-387-72203-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4419-2469-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of these disorders, a central component of the pathophysiology is insulin resistance, i.e., reduced responsiveness to insulin in tissues such as muscle, fat and liver. Insulin resistance is also closely linked to other common health problems, including obesity, polycystic ovarian disease, hyperlipidemia, hypertension, and atherosclerosis. In this book, we will attempt to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. We explore insulin action at the most basic levels, through complex systems. The book will be appealing to basic and clinical scientists.

Table of contents (4 chapters)

  • Insulin and IGF-I Receptor Structure and Binding Mechanism

    Pierre De Meyts, Waseem Sajid, Jane Palsgaard, Anne-Mette Theede, Lisbeth Gauguin, Hassan Aladdin, Jonathan Whittaker

    Pages 1-32

  • Control of Protein Synthesis by Insulin

    Joseph F. Christian, John C. Lawrence Jr.

    Pages 71-89

  • Insulin Action in the Islet β-Cell

    Rohit N. Kulkarni

    Pages 133-151

  • Central Regulation of Insulin Sensitivity

    Silvana Obici, Rossetti Luciano

    Pages 152-167

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-0-387-72204-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-0-387-72203-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4419-2469-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Mechanisms of Insulin Action
Editors
  • Alan R. Saltiel
  • Jeffrey E. Pessin
Series Title
Medical Intelligence Unit
Copyright
2007
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-0-387-72204-7
DOI
10.1007/978-0-387-72204-7
Hardcover ISBN
978-0-387-72203-0
Softcover ISBN
978-1-4419-2469-8
Edition Number
1
Number of Pages
XI, 214
Topics