Advances in Experimental Medicine and Biology

Current Topics in Innate Immunity

Editors: Lambris, John D. (Ed.)

  • Proceedings of the 4th International Conference on Innate Immunity (June, 2006)
  • Shows how new understanding is applied in practical terms
  • Discusses natural killer cells, mast cells, phagocytes, toll-like receptors, complement, host defense in plants and invertebrates, evasion strategies of microorganisms
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eBook $249.00
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  • ISBN 978-0-387-71767-8
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Hardcover $319.00
price for USA
  • ISBN 978-0-387-71765-4
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Softcover $319.00
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  • ISBN 978-1-4419-2455-1
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About this book

Innate Immunity has long been regarded as the non-specific arm of immune response, acting immediately and in a generic way, to defend the host from infections. In the post genomic era, our knowledge of the innate immune system is enriched by findings on the specificity of innate immune reactions as well as to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or inflammation. Several studies indicate that molecules involved in innate immunity exert functions that are either more complex than previously thought, or go well beyond the innate immune character of the system.

The advent of high-throughput platforms for genome and proteome-wide profiling, together with the enormous amount of raw genetic information that has accumulated in the databases, have stirred new expectations in biomedical research. They have led scientists to revisit established biological systems from a global and integrative perspective. Innate Immunity research is now faced with the challenge of trying to integrate isolated biochemical pathways into complex gene and protein regulatory circuits. In this respect, scientists from around the world convened at the 4th International Conference on Innate Immunity (June 4 - 9, 2006), in Corfu, Greece to discuss recent advances in this fast evolving field.

This volume represents a collection of topics on natural killer cells, mast cells, phagocytes, toll like receptors, complement, host defense in plants and invertebrates, evasion strategies of microorganisms, pathophysiology, protein structures, design of therapeutics, and experimental approaches discussed during the conference.

Table of contents (28 chapters)

  • Toll-like Receptors, Natural Killer Cells and Innate Immunity

    Lauzon, Nicole M. (et al.)

    Pages 1-11

  • In the Thick of the Fray: NK Cells in Inflamed Tissues

    Marcenaro, Emanuela (et al.)

    Pages 12-19

  • Structural Insight into Natural Killer T Cell Receptor Recognition of CD1d

    Borg, Natalie A. (et al.)

    Pages 20-34

  • The Journey of Toll-like Receptors in the Cell

    Halaas, Øyvind (et al.)

    Pages 35-48

  • Differential Regulation of Key Signaling Molecules in Innate Immunity and Human Diseases

    Li, Liwu (et al.)

    Pages 49-61

Buy this book

eBook $249.00
price for USA (gross)
  • ISBN 978-0-387-71767-8
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $319.00
price for USA
  • ISBN 978-0-387-71765-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $319.00
price for USA
  • ISBN 978-1-4419-2455-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Current Topics in Innate Immunity
Editors
  • John D. Lambris
Series Title
Advances in Experimental Medicine and Biology
Series Volume
598
Copyright
2007
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-0-387-71767-8
DOI
10.1007/978-0-387-71767-8
Hardcover ISBN
978-0-387-71765-4
Softcover ISBN
978-1-4419-2455-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XXV, 432
Topics