Advances in Experimental Medicine and Biology

TNF Receptor Associated Factors (TRAFs)

Editors: Wu, Hao (Ed.)

  • The only literature that is entirely devoted to TNF Receptor Associated Factors (TRAFs)
  • Up-to-date on the most recent advances in TRAF signal transduction
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eBook $159.00
price for USA (gross)
  • ISBN 978-0-387-70630-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-0-387-70629-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-1-4419-2420-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the interleukin-1 receptor/Toll-like receptor superfamily and the T-cell receptors. They play important roles in mammalian biology including embryonic development, innate and adaptive immune regulation and maintenance of cellular homeostasis. Agents that manipulate the signaling of these receptors are being used or showing promise towards the treatment and prevention of many human diseases such as rheumatoid arthritis, coronary heart disease, transplantation rejection, insulin resistance, multiple organ failure and cancer.

TNF Receptor Associated Factors is the only literature that is entirely devoted to TRAFs. Almost every aspect of TRAF signaling is covered, including the different TRAF family members, their distinct biological functions, the TRAF structures, their modes of receptor recognition, the signaling mechanisms, and the roles of TRAFs in normal cellular functions and in viral infection. TNF Receptor Associated Factors is intended for a wide audience, including researchers in the field of TRAF signaling and students and postdoctoral fellows learning cell biology and cell signal transduction. This exciting new volume is up to date on the most recent advances in TRAF signal transduction.

Table of contents (15 chapters)

  • Phylogeny of the TRAF/MATH Domain

    Zapata, Juan M. (et al.)

    Pages 1-24

  • TRAF1 and Its Biological Functions

    Lee, Soo Young (et al.)

    Pages 25-31

  • Physiological Roles and Mechanisms of Signaling by TRAF2 and TRAF5

    Au, Ping-Yee Billie (et al.)

    Pages 32-47

  • TRAF3 and Its Biological Function

    He, Jeannie Q. (et al.)

    Pages 48-59

  • TRAF4, the Unique Family Member

    Kedinger, Valérie (et al.)

    Pages 60-71

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-0-387-70630-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-0-387-70629-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-1-4419-2420-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
TNF Receptor Associated Factors (TRAFs)
Editors
  • Hao Wu
Series Title
Advances in Experimental Medicine and Biology
Series Volume
597
Copyright
2007
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-0-387-70630-6
DOI
10.1007/978-0-387-70630-6
Hardcover ISBN
978-0-387-70629-0
Softcover ISBN
978-1-4419-2420-9
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIX, 206
Topics