Genetically Engineered Mice for Cancer Research

design, analysis, pathways, validation and pre-clinical testing

Editors: Green, Jeffrey E., Ried, Thomas (Eds.)

  • Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches
  • This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology
  • Additionally, these models are emerging as important pre-clinical systems in which to test cancer prevention and therapeutic strategies in order to select compounds for testing in clinical trials
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eBook $189.00
price for USA (gross)
  • ISBN 978-0-387-69805-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-0-387-69803-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-1-4899-9125-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology. Additionally, these models are emerging as important pre-clinical systems in which to test cancer prevention and therapeutic strategies in order to select compounds for testing in clinical trials.

Table of contents (28 chapters)

  • Overview of Designing Genetically Engineered Mouse (GEM) Models

    Doetschman, Thomas (et al.)

    Pages 1-15

  • The Use of Cre–loxP Technology and Inducible Systems to Generate Mouse Models of Cancer

    Deng, Chu-Xia

    Pages 17-36

  • Using Recombineering Technology to Create Genetically Engineered Mouse Models

    Philip, Subha (et al.)

    Pages 37-56

  • Insertional Mutagenesis for Generating Mouse Models of Cancer

    Largaespada, David A.

    Pages 57-82

  • The RCAS/TVA Somatic Gene Transfer Method in Modeling Human Cancer

    Li, Yi (et al.)

    Pages 83-111

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-0-387-69805-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-0-387-69803-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-1-4899-9125-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Genetically Engineered Mice for Cancer Research
Book Subtitle
design, analysis, pathways, validation and pre-clinical testing
Editors
  • Jeffrey E. Green
  • Thomas Ried
Copyright
2012
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-0-387-69805-2
DOI
10.1007/978-0-387-69805-2
Hardcover ISBN
978-0-387-69803-8
Softcover ISBN
978-1-4899-9125-6
Edition Number
1
Number of Pages
XX, 632
Topics