Applied Bioinformatics and Biostatistics in Cancer Research

Modern Molecular Biology:

Approaches for Unbiased Discovery in Cancer Research

Editors: Yegnasubramanian, Srinivasan, Isaacs, William B. (Eds.)

  • Provides an overview of modern molecular biological approaches to unbiased discovery in cancer research Offers an overview on advances in molecular biology allowing unbiased analysis of changes in cancer initiation and progression Examines strategies employed in modern genomics, gene expression analysis, and proteomics

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eBook $229.00
price for USA (gross)
  • ISBN 978-0-387-69745-1
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  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-0-387-69744-4
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  • Usually dispatched within 3 to 5 business days.
Softcover $299.00
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  • ISBN 978-1-4614-2657-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

A convergence of advancements in molecular biology, engineering, computer science, biostatistics and other disciplines has made possible the development of technologies facilitating the massively parallel investigation of the complex biological phenomena driving cancer initiation and progression. Such technologies include DNA microarrays, next generation sequencing, proteomics technologies, and tissue microarrays. In order to properly harness these technologies to imaginatively decipher these complex biological processes, scientists must have an understanding of the underlying technology, be able to adapt these technologies with molecular biology lab approaches, and then be poised to efficiently process and interpret the extremely high dimensional and complex data sets that are generated by these technologies. The primary purpose of this volume is to help bridge the gap between molecular biologists and cancer researchers and the bioinformatics and computational biology researchers by providing an overview of these technologies to those that are not yet familiar with them.

Table of contents (8 chapters)

  • Genome-Scale Analysis of Data from High-Throughput Technologies

    Wheelan, Sarah J.

    Pages 1-11

  • Analysis of Inherited and Acquired Genetic Variation

    Yegnasubramanian, Srinivasan (et al.)

    Pages 13-31

  • Examining DNA–Protein Interactions with Genome-Wide Chromatin Immunoprecipitation Analysis

    Ballestar, Esteban (et al.)

    Pages 33-45

  • Genome-Wide DNA Methylation Analysis in Cancer Research

    Yegnasubramanian, Srinivasan (et al.)

    Pages 47-66

  • Use of Expression Microarrays in Cancer Research

    Luo, Jun (et al.)

    Pages 67-85

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-0-387-69745-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-0-387-69744-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $299.00
price for USA
  • ISBN 978-1-4614-2657-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Modern Molecular Biology:
Book Subtitle
Approaches for Unbiased Discovery in Cancer Research
Editors
  • Srinivasan Yegnasubramanian
  • William B. Isaacs
Series Title
Applied Bioinformatics and Biostatistics in Cancer Research
Copyright
2010
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-0-387-69745-1
DOI
10.1007/978-0-387-69745-1
Hardcover ISBN
978-0-387-69744-4
Softcover ISBN
978-1-4614-2657-8
Series ISSN
2363-9644
Edition Number
1
Number of Pages
XII, 192
Topics