Protein Reviews

Protein Misfolding, Aggregation and Conformational Diseases

Part B: Molecular Mechanisms of Conformational Diseases

Editors: Uversky, Vladimir N., Fink, Anthony (Eds.)

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eBook $269.00
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  • ISBN 978-0-387-36534-3
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Hardcover $339.00
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  • ISBN 978-0-387-36529-9
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Softcover $339.00
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  • ISBN 978-1-4419-4216-6
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About this book

Protein Misfolding, Aggregation and Conformational Diseases, Part B: Molecular Mechanisms of Conformational Diseases, is a comprehensive volume providing a broad and detailed discussion of the relationships of protein misfolding and aggregation with the pathogenesis of numerous conformational diseases. While the Part A was dedicated to the description of the general mechanisms underlying protein misfolding, aggregation, and development of protein deposition disorders, this volume summarizes recent achievements in the understanding of the molecular mechanisms of conformational diseases. Research indicates that these mechanisms are highly diverse and range from the altered protein structure leading to the enhanced propensity for aggregation/deposition or the impaired functions and ending with changes in supra-molecular structures or posttranslational modification. Protein Misfolding, Aggregation and Conformational Diseases, Part B: Molecular Mechanisms of Conformational Diseases, is an ideal book for pharmaceutical scientists, molecular and cellular biologists, biochemists, immunologists, protein scientists, and biophysicists.

Table of contents (9 chapters)

  • The Pathogenesis of Alzheimer’s Disease: General Overview

    Liana G. Apostolova, Jeffrey L. Cummings

    Pages 3-29

  • α-Synuclein Aggregation and Parkinson’s Disease

    Vladimir N. Uversky

    Pages 61-110

  • Immunoglobulin Light Chain and Systemic Light-Chain Amyloidosis

    Marina Ramirez-Alvarado, Janelle K. De Stigter, Elizabeth M. Baden, Laura A. Sikkink, Richard W. McLaughlin, Anya L. Taboas

    Pages 183-197

  • Pancreatic Islet Amyloid and Diabetes

    Anne Clark, Jenni Moffitt

    Pages 199-216

  • Transthyretin and the Transthyretin Amyloidoses

    Joel N. Buxbaum

    Pages 259-283

Buy this book

eBook $269.00
price for USA (gross)
  • ISBN 978-0-387-36534-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $339.00
price for USA
  • ISBN 978-0-387-36529-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $339.00
price for USA
  • ISBN 978-1-4419-4216-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Protein Misfolding, Aggregation and Conformational Diseases
Book Subtitle
Part B: Molecular Mechanisms of Conformational Diseases
Editors
  • Vladimir N. Uversky
  • Anthony Fink
Series Title
Protein Reviews
Series Volume
6
Copyright
2007
Publisher
Springer US
Copyright Holder
Springer-Verlag US
eBook ISBN
978-0-387-36534-3
DOI
10.1007/978-0-387-36534-3
Hardcover ISBN
978-0-387-36529-9
Softcover ISBN
978-1-4419-4216-6
Edition Number
1
Number of Pages
XXVI, 538
Number of Illustrations and Tables
98 b/w illustrations, 14 illustrations in colour
Topics