Overview
- Brings together the disciplines of Biopharmaceutics, Pharmacokinetics and Pharmacodynamics (BPP)
- Coveres the theory with specific examples behind all three under the perspective of heterogeneous processes while also treating the current state of the art in applied and theoretical BPP
- Can serve as a text for graduate courses in bioengineering or BPP and as working tool for the empirical scientist who wants to expand into theory or the mathematician working in the biopharmaceutical field
- Includes supplementary material: sn.pub/extras
Part of the book series: Interdisciplinary Applied Mathematics (IAM, volume 30)
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Table of contents (11 chapters)
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Front Matter
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Basic Concepts
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Front Matter
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Modeling in Biopharmaceutics
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Front Matter
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Modeling in Pharmacokinetics
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Front Matter
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Modeling in Pharmacodynamics
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Front Matter
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Back Matter
Keywords
About this book
The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods.
This timely and useful book will appeal to graduate students and researchers in pharmacology, pharmaceutical sciences, bioengineering, and physiology.
Reviews
From the reviews:
"This book presents a novel modelling approach to biopharamceutics, pharmacokinetics and pharmacodynamic phenomena. … This state-of-the-art volume will be helpful to students and researchers in pharmacology, bioengineering, and physiology. This book is a must for pharmaceutical researchers to keep up with recent developments in this field." (P. R. Parthasarathy, Zentralblatt MATH, Vol. 1103 (5), 2007)
Authors and Affiliations
Bibliographic Information
Book Title: Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics
Book Subtitle: Homogeneous and Heterogeneous Approaches
Authors: Panos Macheras, Athanassios Iliadis
Series Title: Interdisciplinary Applied Mathematics
DOI: https://doi.org/10.1007/0-387-31910-7
Publisher: Springer New York, NY
eBook Packages: Mathematics and Statistics, Mathematics and Statistics (R0)
Copyright Information: Springer-Verlag New York 2006
eBook ISBN: 978-0-387-31910-0Published: 26 April 2006
Series ISSN: 0939-6047
Series E-ISSN: 2196-9973
Edition Number: 1
Number of Pages: XX, 444
Topics: Mathematical and Computational Biology, Pharmacology/Toxicology, Biological and Medical Physics, Biophysics, Biomedical Engineering and Bioengineering, Biochemistry, general, Applications of Mathematics