Endocrine Updates

Leptin

Editors: Castracane, V. Daniel, Henson, Michael C. (Eds.)

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  • ISBN 978-0-387-31416-7
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Hardcover $259.00
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  • ISBN 978-0-387-31415-0
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About this book

The discovery of leptin little more than a decade ago, as a hormone produced in white adipose tissue with an important role in satiety and energy expenditure, was a seminal event in our understanding of adiposity. This initial advance in the new endocrinology of obesity was soon followed by the realization that leptin was not only produced in adipose tissue, but in many different tissues of the body, and that receptors were similarly distributed. Additionally, the early recognition of infertility that was associated with leptin deficiency prompted research that identified roles for the polypeptide in virtually every area of reproductive biology.

A general interest in leptin has rapidly produced inroads into unexpected areas of physiology that may eventually elucidate the varied relationships of adiposity to human health and disease. These developments have been paralleled by a rigorous investigation as a product of pharmaceutical interest. The broad range of physiology and the clinical situations in which leptin is now implicated is reviewed for the first time in the present volume.

 

***Series Editor's comments****

This volume integrates cutting edge basic and clinical information encompassing the expression of leptin and leptin receptors, pathophysiology and clinical role of leptin- a new neuroendocrine hormone with pleiotropic roles in appetite regulation, metabolic, inflammatory, neoplastic, cardiovascular and reproductive functions.

This single volume encyclopedic coverage is indispensable to students, postdoctoral trainees, fellows, scientists and practitioners interested in neuroendocrine peptide control of multiple cellular functions.

Shlomo Melmed, M.D.
Series Editor
Endocrine Updates

 

Reviews

From the reviews:

"This book is unique among reviews on leptin because it covers a number of different areas, and does so well. … Overall, the book serves as an excellent resource for students and researchers and will provide an accessible starting point for more in-depth reading of the primary literature for a given topic." (Matthew J. Brady, Doody’s Electronic Journal, January, 2007)


Table of contents (4 chapters)

  • The Obese (ob/ob) Mouse and the Discovery of Leptin

    V. Daniel Castracane, Michael C. Henson

    Pages 1-9

  • Leptin and Other Endocrine Systems

    Robert V. Considine

    Pages 103-123

  • Leptin and Cancer

    Delia-Marina Alexe, Eleni Petridou

    Pages 201-223

  • Pulsatile and Diurnal Leptin Rhythms

    Luciana Ribeiro, João Vicente Busnello, Julio Licínio

    Pages 247-262

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-0-387-31416-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-0-387-31415-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-1-4419-4065-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Leptin
Editors
  • V. Daniel Castracane
  • Michael C. Henson
Series Title
Endocrine Updates
Series Volume
25
Copyright
2007
Publisher
Springer US
Copyright Holder
Springer-Verlag US
eBook ISBN
978-0-387-31416-7
DOI
10.1007/978-0-387-31416-7
Hardcover ISBN
978-0-387-31415-0
Softcover ISBN
978-1-4419-4065-0
Series ISSN
1566-0729
Edition Number
1
Number of Pages
XIV, 372
Number of Illustrations and Tables
22 b/w illustrations, 9 illustrations in colour
Topics