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Biochemistry of Atherosclerosis

  • Book
  • © 2006

Overview

Editors:
  1. Sukhinder Kaur Cheema

    1. Department of Biochemistry, Memorial University of Newfoundland, St. John's NL, Canada

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  • Biochemistry of Atherosclerosis discusses emerging concepts in the pathogenesis of and therapeautic approaches to atherosclerosis. This up-to-date volume examines in detail all aspects of atherogenesis. This book is valuable reading for all biomedical researchers.
  • Biochemistry of Atherosclerosis is the first volume in the new series, Advances in Biochemistry in Health and Disease, edited by Dr. Naranjan S. Dhalla. This series will focus on developments in biochemical research with implications for health and disease. The series will consist of original edited volumes, monographs, references, proceedings.
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Biochemistry in Health and Disease (ABHD, volume 1)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-xv
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  2. Hyperlipidaemia and Atherosclerosis

    1. Front Matter

      Pages 1-1
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    2. Reverse Cholesterol Transport

      • Jim W. Burgess, Philip A. Sinclair, Christophe M. Chretien, Jonathon Boucher, Daniel L. Sparks
      Pages 3-22

    3. The Role of LCAT in Atherosclerosis

      • Dominic S. Ng
      Pages 23-38

    4. Howdy Partner: Apolipoprotein A-I-ABCA1 Interactions Mediating HDL Particle Formation

      • Sereyrath Ngeth, Gordon A. Francis
      Pages 39-52

    5. Role of the Scavenger Receptor Class B Type I in Lipoprotein Metabolism and Atherosclerosis: Insight from Genetically Altered Mice

      • Bernardo Trigatti
      Pages 53-69

    6. The Role of Scavenger Receptors in Signaling, Inflammation and Atherosclerosis

      • Daisy Sahoo, Victor A. Drover
      Pages 70-91

    7. ABC Transporters and Apolipoprotein E: Critical Players in Macrophage Cholesterol Efflux and Atherosclerosis

      • Kathryn E. Naus, Cheryl L. Wellington
      Pages 92-120

    8. Provision of Lipids for Very Low-Density Lipoprotein Assembly

      • Dean Gilham, Richard Lehner
      Pages 121-149

    9. Oxidatively Modified Low-Density Lipoproteins and Thrombosis

      • Garry X. Shen
      Pages 150-167

    10. The Clinical Significance of Small, Dense Low-Density Lipoproteins

      • Manfredi Rizzo, Kaspar Berneis
      Pages 168-185

    11. Bile Acids: At the Crossroads of Sterol, Fat and Carbohydrate Metabolism

      • Luis B. Agellon
      Pages 186-201

  3. Diabetes and Hypertension Induced Atherosclerosis

    1. Front Matter

      Pages 203-203
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    2. Lipoprotein Metabolism in Insulin-Resistant States

      • Rita Kohen Avramoglu, Heather Basciano, Khosrow Adeli
      Pages 205-246

    3. The Roles of Protein Glycation, Glycoxidation, and Advanced Glycation End-Product Formation in Diabetes-Induced Atherosclerosis

      • Imran Rashid, Bronwyn E. Brown, David M. van Reyk, Michael J. Davies
      Pages 247-283

    4. Molecular and Cellular Mechanisms by Which Diabetes Mellitus Promotes the Development of Atherosclerosis

      • Geoff H. Werstuck
      Pages 284-304

    5. Hypertension and Atherosclerosis: Advanced Glycation End Products—A Common Link

      • Sudesh Vasdev, Vicki Gill
      Pages 305-326

  4. Hyperhomocysteinemia and Atherosclerosis

    1. Front Matter

      Pages 327-327
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    2. Homocysteine Metabolism

      • Enoka P. Wijekoon, Margaret E. Brosnan, John T. Brosnan
      Pages 329-357

    3. Role of Hyperhomocysteinemia in Atherosclerosis

      • Stephen M. Colgan, Donald W. Jacobsen, Richard C. Austin
      Pages 358-379
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Keywords

About this book

At its present rate of growth, atherosclerosis will be the major cause of death from disease by the year 2020. Atherosclerosis is an extremely complex, biochemical, multifactorial process. This book will cover many aspects of atherogenesis, with particular emphasis on lipid and lipoprotein metabolism. We will cover all aspects of the regulation of cholesterol homeostasis and the importance of each pathway. This book will explore the role of nuclear hormone receptors on lipid and lipoprotein metabolism and their complex roles in atherogenesis. Finally, how the use of genetic studies can help sort out the immense complexities that mediate these aspects of atherogenesis will be discussed.

Editors and Affiliations

  • Department of Biochemistry, Memorial University of Newfoundland, St. John's NL, Canada

    Sukhinder Kaur Cheema

About the editor

Dr. Sukhinder K. Cheema is Associate Professor of Biochemistry, Memorial University of Newfoundland, Canada. She has worked as a Research Scientist with the Nova-Husky Research Corporation in Alberta, Canada. She is currently researching the molecular mechanisms of cholesterol ester transfer protein regulation by dietary fats and hormones. She also researches the regulation of genes involved in cholesterol metabolism by hormone factors, the molecular basis of diabetes-accelerated atherosclerosis, and the mechanisms of lipid abnormalities caused by protease inhibitors.

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