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  • Book
  • © 2007

Tumors of the Brain and Spine

  • Focuses primarily on the standard approaches to the treatment of benign, primary low-grade to high-grade, and metastatic tumors in the brain and spine
  • Overview on treatment with focus on neurosurgery, chemotherapy, and radiation therapy, both singly and in combination.
  • Reviews symptom management, molecular genetics and neuropathology of intracranial tumors, leptomeningeal dissemination of systemic cancer, and epidemiology of brain tumors
  • Provides innovative treatment strategies
  • Includes supplementary material: sn.pub/extras

Part of the book series: MD Anderson Cancer Care Series (MDCCS)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xii
  2. Epidemiology of Brain Tumors

    • Melissa L. Bondy, Randa El-Zein, Michael E. Scheurer
    Pages 1-22
  3. Neuropathology and Molecular Biology of Intracranial Tumors

    • Gregory N. Fuller, Kenneth D. Aldape
    Pages 23-35
  4. Radiology of Brain Tumors: Structure and Physiology

    • J. Matthew Debnam, Leena Ketonen, Leena M. Hamberg, George J. Hunter
    Pages 37-52
  5. Surgically Curable Brain Tumors of Adults

    • Franco DeMonte
    Pages 53-92
  6. Surgical Strategies for High-Grade Gliomas

    • Sujit S. Prabhu
    Pages 121-133
  7. Cytotoxic Chemotherapy for Diffuse Gliomas

    • Ivo W. Tremont-Lukats, Mark R. Gilbert
    Pages 153-170
  8. Innovative Treatment Strategies for High-Grade Gliomas

    • Charles A. Conrad, Amy B. Heimberger
    Pages 171-190
  9. Pituitary Tumors in Oncology

    • Ian E. McCutcheon
    Pages 191-223
  10. Neoplastic Meningitis

    • Morris D. Groves
    Pages 245-261
  11. Tumors of the Extradural Spine

    • Ehud Mendel
    Pages 273-294
  12. Tumors of the Spinal Cord and Intradural Space

    • Laurence D. Rhines, Morris D. Groves
    Pages 295-328
  13. Symptom Management for Patients with Brain Tumors: Improving Quality of Life

    • Allen W. Burton, Tracy L. Veramonti, Phillip C. Phan, Jeffrey S. Wefel
    Pages 329-351
  14. Back Matter

    Pages 353-364

About this book

It is frequently stated that progress in the management of tumors of the brain and spine has not occurred in the past 25 years. Such statements seriously underestimate and misrepresent progress in managing various central nervous system tumors, the tremendous technologic enhancements that have revolutionized the imaging of the tumors and the host organ, the multitude of surgical adjuncts such as computerized imaging guidance and functional mapping of the brain and its tracts that are routinely used in the modern neurosurgical operating room, and the highly conformal delivery of radiation to the tumor mass with remarkable sparing of the surrounding nervous tissue. Underlying these technologic improvements are the changes in philosophy that have resulted in a true multidisciplinary approach. Equally significant is the molecular revolution that is identifying key markers behind the genesis of brain tumors, their proliferation, and their resistance to therapy. These molecular discoveries have ushered in the era of molecular targeted therapy, as first demonstrated by the extraordinary success story in chronic myelogenous leukemia of imatinib (Gleevec). The rational combination of targeted agents will revolutionize the way che- therapy is given, either alone or in conjunction with radiotherapy. Lastly, focused attention to patients’ well-being has emphasized all measures of quality of life, has encouraged greater participation by patients and their caregivers in the decision-making process, and has encouraged the development of a variety of quality-of-life measurement tools to ensure that adverse effects of treatment are recognized and addressed.

Editors and Affiliations

  • The University of Texas M. D. Anderson Cancer Center, Houston, USA

    Franco DeMonte, Mark R. Gilbert, Anita Mahajan, Ian E. McCutcheon, Aman U. Buzdar, Ralph S. Freedman

Bibliographic Information

  • Book Title: Tumors of the Brain and Spine

  • Editors: Franco DeMonte, Mark R. Gilbert, Anita Mahajan, Ian E. McCutcheon, Aman U. Buzdar, Ralph S. Freedman

  • Series Title: MD Anderson Cancer Care Series

  • DOI: https://doi.org/10.1007/978-0-387-29202-1

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag US 2007

  • Softcover ISBN: 978-0-387-29201-4Published: 05 June 2007

  • eBook ISBN: 978-0-387-29202-1Published: 10 May 2007

  • Edition Number: 1

  • Number of Pages: XII, 364

  • Number of Illustrations: 87 b/w illustrations

  • Topics: Neurology, Oncology, Surgical Oncology, Neurosurgery, Pathology

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access