The Science of Flavonoids

1. Front Matter

   Pages i-vii

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2. The Stereochemistry of Flavonoids

   • J. P. J. Marais, B. Deavours, R. A. Dixon, D. Ferreira

   Pages 1-46

3. Isolation and Identification of Flavonoids

   • M. Stobiecki, P. Kachlicki

   Pages 47-69

4. The Biosynthesis of Flavonoids

   • B. S. J. Winkel

   Pages 71-95

5. The Regulation of Flavonoid Biosynthesis

   • F. Quattrocchio, A. Baudry, L. Lepiniec, E. Grotewold

   Pages 97-122

6. Transport of Flavonoids: From Cytosolic Synthesis to Vacuolar Accumulation

   • S. Kitamura

   Pages 123-146

7. Flavonoid Pigments as Tools in Molecular Genetics

   • S. Chopra, A. Hoshino, J. Boddu, S. Iida

   Pages 147-173

8. The Evolution of Flavonoids and Their Genes

   • M. D. Rausher

   Pages 175-211

9. Flavonoids as Nutraceuticals

   • J-K. Lin, M-S. Weng

   Pages 213-238

10. Flavonoids as Signal Molecules: Targets of Flavonoid Action

    • W. A. Peer, A. S. Murphy

    Pages 239-268

11. Back Matter

    Pages 269-273

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Despite the historical signifigance of flavonoids and their pigments in establishing the basis for modern genetics, research in this large group of secondary metabolites continues to be more intense than ever. While research has focused in the past primarily on the chemistry and biosynthesis of flavonoids, the past few years have witnessed increasing research in the applications of flavonoids as nutraceuticals and pharmaceuticals as well as on their roles as signal molecules within plants and between plants and other organisms. No book has tried to provide a comprehensive overview of the flavonoid field since 1990.

This book will comprehensively cover the emerging areas in the field of flavonoid research and their applications. First, flavonoids must be introduced as chemical entities and then an overview of the tools currently available for their analysis will be presented.

• Cytosol
• Evolution
• Grotewold
• Regulation
• Transport
• currentjks
• flavonoids
• isoflavone
• plant science
• transcription

• Department of Cellular and Molecular Biology, The Ohio State University, Columbus, USA

  Erich Grotewold

Dr. Grotewold is an Associate Professor of Plant Biology at The Ohio State University. He received his Ph.D from the Instituto de Ingenieria Genetics y Bologia Molecular, University of Buenos Aires, Argentina in 1988. His research focuses on Regulation of Gene Expression; Function and Evolution of Myb Proteins; Plant Metabolic Engineering. Combining molecular, cellular, biochemical and genetic approaches, his laboratory investigates fundamental questions regarding the mechanisms by which plants control gene expression, and how transcription factors have impacted plant evolution and speciation. He has started to develop regulatory networks in Arabidopsis that should help explain how the 28,000+ Arabidopsis genes are expressed. In addition, he is utilizing his extensive knowledge on transcription factors for plant metabolic engineering.

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