Protein Reviews

Protein Misfolding, Aggregation and Conformational Diseases

Part A: Protein Aggregation and Conformational Diseases

Editors: Uversky, Vladimir N., Fink, Anthony (Eds.)

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eBook $229.00
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  • ISBN 978-0-387-25919-2
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  • ISBN 978-0-387-25918-5
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About this book

Protein Misfolding, Aggregation, and Conformational Disease, is the first book to discuss significant achievements in protein structure-function relationships in the areas of biochemistry, molecular biology and molecular medicine. This volume summarizes recent achievements in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders. Research indicates that various human disorders, including most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. Protein Misfolding, Aggregation and Conformational Diseases is an ideal book for biochemists, protein scientists, immunologists, pharmaceutical scientists, and molecular and cellular biologists.

Table of contents (19 chapters)

  • Structural and Conformational Prerequisites of Amyloidogenesis

    Uversky, Vladimir N. (et al.)

    Pages 1-20

  • The Generic Nature of Protein Folding and Misfolding

    Dobson, Christopher M.

    Pages 21-41

  • Relative Importance of Hydrophobicity, Net Charge, and Secondary Structure Propensities in Protein Aggregation

    Chiti, Fabrizio

    Pages 43-59

  • Cytotoxic Intermediates in the Fibrillation Pathway: Aβ Oligomers in Alzheimer’s Disease as a Case Study

    Klein, William L.

    Pages 60-81

  • Glycosaminoglycans, Proteoglycans, and Conformational Disorders

    Cole, Gregory J. (et al.)

    Pages 83-100

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-0-387-25919-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-0-387-25918-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4419-3851-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Protein Misfolding, Aggregation and Conformational Diseases
Book Subtitle
Part A: Protein Aggregation and Conformational Diseases
Editors
  • Vladimir N. Uversky
  • Anthony Fink
Series Title
Protein Reviews
Series Volume
4
Copyright
2006
Publisher
Springer US
Copyright Holder
Springer-Verlag US
eBook ISBN
978-0-387-25919-2
DOI
10.1007/b136464
Hardcover ISBN
978-0-387-25918-5
Softcover ISBN
978-1-4419-3851-0
Edition Number
1
Number of Pages
XVIII, 419
Topics