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In vivo Models of HIV Disease and Control

  • Book
  • © 2006

Overview

Editors:
  1. Herman Friedman

    1. Department of Medical Microbiology and Immunology, University of South Florida College of Medicine, Tampa, USA

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  2. Steven Specter

    1. Department of Medical Microbiology and Immunology, University of South Florida College of Medicine, Tampa, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Mauro Bendinelli

    1. Department of Experimental Pathology and Retrovirus Center, University of Pisa, Pisa, Italy

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    You can also search for this editor in PubMed   Google Scholar

  • This is the first and only comprehensive review volume describing the various immunodeficiency virus diseases in animal models, especially as related to the human AIDS situation
  • Includes supplementary material: sn.pub/extras

Part of the book series: Infectious Agents and Pathogenesis (IAPA)

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Historical Perspective

    • Murray B. Gardner
    Pages 1-18

  3. Animal Model Systems of HIV-Diseases

    • Eric R. Anderson, Huangui Xiong, Howard E. Gendelman
    Pages 19-43

  4. Chemokines and Their Receptors and the Neuropathogenesis of HIV-1 Infection

    • Howard E. Gendelman, Eric R. Anderson, Loyda Melendez, Jialin Zheng
    Pages 45-80

  5. SCID Mice Transplanted With Human Cells as Small Animal Models in AIDS Research

    • Caterina Lapenta, Stefano M. Santini, Massimo Spada, Filippo Belardelli
    Pages 81-99

  6. SIV as a Model for AIDS Pathogenesis Studies

    • Ulrike Sauermann, Sieghart Sopper
    Pages 101-119

  7. SIV Infection of Macaques as a Model for AIDS Drug Studies

    • Koen K. A. van Rompay, Raman P. Singh, Marta L. Marthas
    Pages 121-147

  8. FIV as a Model for HIV: An Overview

    • Ellen E. Sparger
    Pages 149-237

  9. FIV as a Model for AIDS Pathogenesis Studies

    • Thomas W. Vahlenkamp, Mary B. Tompkins, Wayne A. F. Tompkins
    Pages 239-273

  10. Drugs of Abuse, AIDS, and the FIV Model

    • Margaret C. Barr, Maria Pia Testa, Tom R. Phillips
    Pages 275-291

  11. FIV as a Model for AIDS Vaccine Studies

    • Stephen Dunham, Oswald Jarrett
    Pages 293-332

  12. FIV as a Model for HIV Treatment

    • Katrin Hartmann, Christiane Stengel
    Pages 333-364

  13. Equine Infectious Anemia Virus as a Model for Lentiviral Pathogenesis

    • Susan L. Payne, Wah-Seng Lim, Frederick J. Fuller, Judith M. Ball
    Pages 365-390

  14. Studies of the Structure of Caprine Arthritis-Encephalitis Virus Surface Envelope Glycoprotein

    • Isidro Hötzel, William P. Cheevers
    Pages 391-403

  15. Ethical Issues in the Use of Animal Models of Infection and Some Practical Refinements

    • David B. Morton
    Pages 405-424

  16. Future Perspectives

    • Mauro Pistello
    Pages 425-428

  17. Back Matter

    Pages 429-436
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Keywords

About this book

An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, treatment, vaccine development and many other aspects of HIV.

Part of the series Infectious Agents and Pathogenesis, this volume reviews the immune deficiency virus in a variety of hosts. Pathogenesis, vaccine and drug development, epidemiology, and the natural history of the monkey, mouse, cat, cow, horse, and other animal viruses are detailed and compared to HIV. Also included are chapters on the history and future of animal models, as well as a chapter on ethical and safety considerations in using animal models for AIDS studies.

Editors and Affiliations

  • Department of Medical Microbiology and Immunology, University of South Florida College of Medicine, Tampa, USA

    Herman Friedman, Steven Specter

  • Department of Experimental Pathology and Retrovirus Center, University of Pisa, Pisa, Italy

    Mauro Bendinelli

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