Metabolome Analyses:

Strategies for Systems Biology

Editors: Vaidyanathan, Seetharaman, Harrigan, George G., Goodacre, Royston (Eds.)

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eBook $189.00
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  • ISBN 978-0-387-25240-7
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Hardcover $249.00
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  • ISBN 978-0-387-25239-1
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  • ISBN 978-1-4419-3780-3
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About this book

Metabolome Analyses is intended as a follow-up to Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis (Kluwer, 2003). That text offered guidelines to currently available technology, bioinformatics and databases. Evidence was presented showing metabolic profiling as a valuable addition to genomics and proteomics strategies devoted to drug discovery and development. This book focuses on how metabolic profiling is being more comprehensively integrated with the other "omics" technologies. It provides more practical applications of such "panomics" or "Systems Biology" approaches. The expanding use of mass spectrometry as a measurement technology in metabolic profiling is addressed through demonstrated applications. The integration of metabolic profiling and proteomics is probably most developed for plant-based studies, which was not addressed in Volume 1. Other areas related to metabolic profiling continue to show significant development. These include database strategies and an increased acceptance by the pharmaceutical industry of metabolic profiling. Also covered is the use of in silico metabolic networks. Again the focus is primarily on the pharmaceutical industry but the importance of metabolic profiling to studies on human nutrition (a burgeoning area) is discussed.

The primary audience for Metabolome Analyses consists of academics (professors, post-doctoral researchers) involved in metabolic analyses, genomics transcriptomics, proteomics, bioinformatics; and corresponding researchers in the pharmaceutical and biotechnology industries (including Big Pharma, mid –capital and small venture-capital based enterprises) and in research institutes.

Table of contents (5 chapters)

  • Towards Integrative Functional Genomics Using Yeast as a Reference Model

    Juan I. Castrillo, Stephen G. Oliver

    Pages 9-29

  • Metabolite Profiling with GC-MS and LC-MS

    Ralf Looser, Amo J. Krotzky, Richard N. Trethewey

    Pages 103-118

  • Parallel Metabolite and Transcript Profiling

    Alisdair R. Fernie, Ewa Urbanczyk-Wochniak, Lothar Willmitzer

    Pages 291-306

  • How Lipidomic Approaches Will Benefit the Pharmaceutical Industry

    Alvin Berger

    Pages 349-365

  • Metabolites and Fungal Virulence

    Edward M. Driggers, Axel A. Brakhage

    Pages 367-381

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-0-387-25240-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-0-387-25239-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4419-3780-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Metabolome Analyses:
Book Subtitle
Strategies for Systems Biology
Editors
  • Seetharaman Vaidyanathan
  • George G. Harrigan
  • Royston Goodacre
Copyright
2005
Publisher
Springer US
Copyright Holder
Springer-Verlag US
eBook ISBN
978-0-387-25240-7
DOI
10.1007/b106967
Hardcover ISBN
978-0-387-25239-1
Softcover ISBN
978-1-4419-3780-3
Edition Number
1
Number of Pages
XXII, 390
Topics