Cancer Genetics

Genetics of Colorectal Cancer

Editors: Potter, John D., Lindor, Noralane M. (Eds.)

  • Will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers

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eBook $199.00
price for USA (gross)
  • ISBN 978-0-387-09568-4
  • Digitally watermarked, DRM-free
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  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-0-387-09567-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-1-4419-1865-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The last 20 years have seen a remarkable increase in knowledge of the etiology of colorectal cancer. At least three aspects are much clearer. First, known environmental agents and behaviors have been identified that increase risk (for example, diets high in meat, obesity, and smoking ) or decrease risk (for example, diets high in plant foods, aspirin, and physical activity) of colorectal cancer. Second, germline mutations in specific genes have been identified for the major inherited syndromes involving colorectal cancer (FAP, Lynch Syndrome, Juvenile Polyposis, MYH-Associated Polyposis, Li-Fraumeni Syndrome) as have variants of genes that modify the risk associated with the known environmental agents. Third, the specific tissue, cellular, and molecular disturbances that characterize the progression to different subtypes of colorectal cancer have been recently described. Genetics of Colorectal Cancer provides the most up-to-date information in each of these areas.

Table of contents (13 chapters)

  • Colorectal Cancer: Epidemiology

    Potter, John D. (et al.)

    Pages 5-25

  • Mouse Models of Intestinal Cancer

    Perchiniak, Erin M. (et al.)

    Pages 27-49

  • The Chromosomal-Instability Pathway and APC Gene Mutation in Colorectal Cancer

    Gryfe, Robert

    Pages 53-72

  • DNA Methylation in Colorectal Cancer: Multiple Facets of Tumorigenesis

    Young, Joanne P. (et al.)

    Pages 73-95

  • Pathways and Pathology

    Jass, Jeremy R.

    Pages 97-121

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-0-387-09568-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-0-387-09567-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-1-4419-1865-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Genetics of Colorectal Cancer
Editors
  • John D. Potter
  • Noralane M. Lindor
Series Title
Cancer Genetics
Copyright
2009
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-0-387-09568-4
DOI
10.1007/978-0-387-09568-4
Hardcover ISBN
978-0-387-09567-7
Softcover ISBN
978-1-4419-1865-9
Edition Number
1
Number of Pages
XI, 309
Topics